The Effect of Fecal Microbiota Transplantation in Ulcerative Colitis
The Effect of Fecal Microbiota Transplantation in Ulcerative Colitis - A Case Study
7 patients with active Ulcerative Colitis are treated with 25 multi-donor FMT Capsules daily for 50 days.
7 patients with active Ulcerative Colitis are treated with 25 multi-donor FMT Capsules daily for 50 days All patients are followed with regular follow up after 2,4,8,12,16, 20 and 24 weeks.
Inclusion Criteria: Diagnosed with Ulcerative Colitis (UC) SCCAI between 4 and 10 at inclusion On a stable dose of 5-aminosalicylic acid (5-ASA) or without current treatment. Previous treatment with glucocorticoids, thiopurines and/or biological treatment was accepted. Fecal Calprotectin > 250 mg/kg Colonoscopy performed within the last 3 years Capable of writing and speaking Danish Attending regular follow-ups by a specialist in gastroenterology. Exclusion Criteria: Biological treatment within the last four weeks Treatment with antibiotics within 48 hours before intervention Alcohol use above current Danish guidelines (14 units/week for men and 7 units/week for women) Pregnancy or planned pregnancy Active cancer disease Medical treatment of mental disorder Other chronic gastroenterological disorder besides UC, Irritable Bowel Syndrome (IBS) or Reflux-disease.