Efficacy of External Nasal Nerve Block in Prevention of Postoperative Agitation Following Nasal Surgeries
Efficacy of External Nasal Nerve Block on Postoperative Agitation Following Nasal Surgeries Under General Anesthesia. Randomized, Controlled Trial
  • Phase

  • Study Type

  • Status

    Completed No Results Posted
  • Intervention/Treatment

    lidocaine epinephrine ...
  • Study Participants

Emergence agitation following general anaesthesia may lead to serious complications like self-extubation or removal of catheters, which can lead to hypoxia, aspiration pneumonia, bleeding or reoperation. Nose surgery is associated with a higher incidence of emergence agitation. The investigators planned to evaluate the efficacy of external nasal nerve block in prevention of postoperative agitation following external nasal surgeries under general anesthesia(GA).
Study Started
Aug 15
Primary Completion
Apr 15
Study Completion
Jul 01
Last Update
Dec 27

Procedure External nasal nerve block

Three single (midline injection) and 4 paired (bilateral injection) sites to block the external nasal sensation.

Drug saline adrenaline

Drug Xylocaine, adrenaline

Group I(control) Placebo Comparator

patients allocated for external nasal nerve block with saline adrenaline 1/200,000 (placebo)

Group II(block) Active Comparator

'External nasal nerve block by Xylocaine, adrenaline'


Inclusion Criteria:

110 adult patients of ASA physical status I and II,
Age 20-60 years,
Scheduled for elective external nasal surgeries in which nasal packing on each side was used postoperatively for 24 hours.

Exclusion Criteria:

History of uncontrolled hypertension,
Ischemic or valvular heart disease,
Use of MAO inhibitors or adrenergic blocking drugs,
Cognitive impairment,
Patients taking antipsychotics,
Renal insufficiency or liver dysfunction
No Results Posted