Adductor Canal Block With Continuous Infusion Versus Intermittent Boluses and Morphine Consumption
Adductor Canal Block With Continuous Infusion Versus Intermittent Boluses and Morphine Consumption: A Randomized, Triple-masked, Controlled Study
  • Phase

    Phase 4
  • Study Type

  • Status

    Completed No Results Posted
  • Intervention/Treatment

    ropivacaine ...
  • Study Participants

The investigators believe sufficient spread to all nerves within the adductor canal-and thereby sufficient analgesia-can only be obtained by bolus injections and not by continuous infusions via a catheter. The aim of the study is to investigate whether an adductor canal block performed as repeated intermittent boluses provides superior pain relief to continuous infusion. The investigators hypothesize that adductor canal block performed as intermittent boluses via a catheter will reduce morphine consumption and pain as well as enhance ambulation and muscle strength compared with continuous infusion.
Study Started
Mar 31
Primary Completion
Sep 30
Study Completion
Sep 30
Last Update
Apr 28

Drug ropivacaine 0.2%

Adductor canal block. Placed immediately postoperative. Intervention stops on POD2 12PM

Intermittent bolus Experimental

ropivacaine 0.2%, 21 ml every 3 hours

Continuous infusion Active Comparator

ropivacaine 0.2%, 7ml/h


Inclusion Criteria:

Patients scheduled for total knee arthroplasty in spinal anesthesia
Patients who gave their written informed consent to participating in the study after having fully understood the contents of the protocol and restrictions
American society of anesthesiologists 1-3
Ability to perform a timed up and go test preoperatively

Exclusion Criteria:

Patients who cannot cooperate
Patients who cannot understand or speak Danish.
Patients with allergy to the medicines used in the study
Patients with a daily intake of strong opioids (morphine, oxycodone, ketobemidone, methadone, fentanyl) during the last 4 weeks
Patients suffering from alcohol and/or drug abuse - based on the investigator's assessment
Rheumatoid arthritis
BMI > 40
Neuromuscular pathology in the lower limbs
No Results Posted