An Assessment of Intra-lesional 3% Polidocanol Solution in the Treatment of Digital Myxoid Cyst
An Assessment of Intra-lesional 3% Polidocanol Solution in the Treatment of Digital Myxoid Cysts
  • Phase

    Phase 4
  • Study Type

  • Status

    Unknown status
  • Intervention/Treatment

    polidocanol ...
  • Study Participants

Digital myxoid cysts arise from degeneration in the connective tissue of the digit joint, usually the last joint of the finger or toe, often due to underlying joint arthritis. They may connect with the joint. Pressure from the cyst can result in deformity of the digit's nail and trauma to the cyst results in leakage of the fluid, representing a potential source of entry for infection. Cysts can be tender and interfere with the digit's function. A variety of treatments are available, from simple extrusion which is rarely successful, to more destructive cryotherapy, infra-red coagulation and formal excision under local anaesthetic. These latter three approaches can result in considerable scarring. Sclerosant injection of polidocanol in one small non-randomised trial has been reported to be a well tolerated efficacious treatment with minimal scarring and long-term resolution. Following a pilot study, the investigators aim to trial this treatment to assess efficacy in a larger population.
Study Started
Jun 30
Primary Completion
May 31
Study Completion
May 31
Last Update
Jun 03

Drug polidocanol

Procedure infra-red coagulation

Procedure cryotherapy

polidocanol Experimental

cryotherapy Active Comparator

infra-red coagulation Active Comparator


Inclusion Criteria:

All patients referred to dermatology in NHS Lothian or NHS Fife who have a visible Digital Myxoid Cyst affective the dital phalynx of the toes or fingers.
The patient must have the ability to give informed consent

Exclusion Criteria:

History of sensitivity to polidocanol or other sclerosants
Age less than 18
Inability to give informed consent
Inability to report side effects experienced
Cyst not clearly visible
Cyst not fluid-filled
No Results Posted