Official Title

Methadone in Post-Herpetic Neuralgia Pain
  • Phase

    Phase 3
  • Study Type

  • Status

    Completed No Results Posted
  • Intervention/Treatment

    methadone ...
  • Study Participants

Neuropathic pain is a common condition and affecting 40 to 70% of the general population. Post-herpetic neuralgia is a condition almost complex and requires a multi modal treatment. Aim: This is a pilot proof-of-principle study designed to evaluate the use of low-dose methadone in post-herpetic neuralgia patients who remained refractory after first and second line treatment for post-herpetic neuralgia (PHN) and had indication for the association of an opioid agent to their current drug regimen.
Study Started
Jan 31
Primary Completion
Feb 28
Study Completion
Mar 31
Last Update
Mar 18

Drug Methadone

patients with post-herpetic neuralgia take methadone or placebo to treat pain symptoms.

Drug Placebo

patients with post-herpetic neuralgia take placebo to treat the pain symptoms.

Methadone Experimental

in this arm patients will take methadone 5mg.

Placebo Experimental

in this arm patients will take placebo pills.


Inclusion Criteria:

Patients with chronic (>6 months) symptomatic PHN
with visual analogical scale >40/100mm
use of first and second line drugs (tricyclic antidepressants, venlafaxine and gabapentinoids)

Exclusion Criteria:

Don't full the criteria above
No Results Posted