Effect of Platelet-rich Fibrin on Rotator Cuff Repair
Platelet-Rich Fibrin for Arthroscopically Repaired Massive Rotator Cuff Tears: A Prospective Randomized Pilot Clinical Trial
Lead SponsorUniversidad Autonoma de Madrid
StatusCompleted No Results Posted
Indication/ConditionRotator Cuff Tears of the Shoulder
The objective of this study was to prospectively evaluate the influence of local application of Platelet Rich Fibrin (PRF) on the functional outcome and integrity of the arthroscopically repaired tendons in patients with massive tears of the rotator cuff.
A prospective, randomized clinical trial was performed on 28 patients (22 females, 6 males) with an average age of 65 years (range, 53 to 77) undergoing complete arthroscopic repair of a massive rotator cuff tear. In 14 patients, after the repair was completed, 6 cc. of PRF (vivostat ®) were locally applied to the repair site. In 14 patients no addition of PRF was performed. All patients underwent an arthro-MRI to evaluate the integrity of the repair and a clinical exam one year after the operation. All patients were then followed clinically at a minimum of 2 years. Functional outcome was evaluated with the Constant and DASH scores.
after the tendon is repaired, no additional procedures are performed and no PRF is administered
7cc. of autologous PRF are locally administered to the repair site after reconstruction of the rotator cuff
the group in which the PRF was administered
repair without PRF
Inclusion Criteria: Massive rotator cuff tears affecting supraspinatus and infraspinatus Failed conservative treatment for at least 6 months No hematologic disorder Exclusion Criteria: Rotator cuff affecting subscapularis chronic infectious disease anemia clot disorders low platelet count history of difficulty in venous puncture