Rubidium-82 PET and Tc-99m-MIBI SPET: A Head to Head Comparison
Diagnosis of Coronary Artery Disease With Rubidium-82 PET and Technetium-99m-MIBI SPET: A Head to Head Comparison, Versus Coronary CT Angiography
  • Phase

    Phase 3
  • Study Type

  • Status

    Completed No Results Posted
  • Study Participants

The main purpose of this study is to compare myocardial perfusion imaging using Rubidium-82 PET with Tc-99m-MIBI SPET, in the evaluation of significant Coronary Artery Disease (CAD).
Study Started
Feb 28
Primary Completion
Nov 30
Study Completion
Nov 30
Last Update
May 14

Drug Rubidium-82

Maximum dose allowed per injection: 2200 MBq Maximum cumulated dose allowed per examination: 4400 MBq Intravenous Use

  • Other names: CardioGen-82

Drug Sestamibi. reconstitution with sodium pertechnetate (99mTc)

Maximum dose allowed per injection: 1000 MBq Intravenous Use

  • Other names: Technescan MIBI

Single arm Other

This is an Head to Head Comparison between Rubidium-82 PET and Tc-99m-MIBI SPET with CTA as gold standard. All the patients will undergo the three imaging protocols.


Inclusion Criteria:

Referred for scintigraphy to assess myocardial ischaemia
Ability to give informed written consent.

Exclusion Criteria:

Impaired capacity to consent
Pregnancy, or breastfeeding
Allergy to iv contrast
Renal failure
Severe Uncontrolled asthma
No Results Posted