Impact of Fish Oil Supplementation in 3rd Trimester of Pregnancy on Maternal and Offspring Health
The aim of the trial is to investigate the effect of daily supplementation with 2.7 grams of long chain n-3 fatty acids during the third trimester of pregnancy. In 1990, 533 pregnant women, while they were in gestational week 30, were randomized to fish oil supplements providing the mentioned amount of long chain n-3 fatty acids, olive oil supplements, or no supplements; they were asked to take the supplements until delivery. Health outcomes were assessed during pregnancy and delivery. Further, offspring health and development has been examined during the ensuring two decades by making linkages to the rich Danish health and administrative registries, by asking the offspring to complete web-based questionnaires, and by examining the offspring physically.
4 1-g gelatine capsules per day providing 2,7 grams long chain n-3 fatty acids
4 1-g gelatine capsules with virgin olive oil
These women received 4 1-g capsules of fish oil per day providing 2,7 grams long chain n-3 fatty acids per day, from gestation week 30 until delivery
These women received 4 1-g capsules with olive oil per day from gestational week 30 until delivery
These women received no capsules with oil
Inclusion Criteria: Healthy pregnant women in gestation week 30 Exclusion Criteria: Bleeding episodes during pregnancy