Rhodiola Rosea for Mental and Physical Fatigue
A Randomized Trial of Rhodiola Rosea for Mental and Physical Fatigue in Nurses
  • Phase

    Phase 2
  • Study Type

  • Status

    Unknown status
  • Study Participants

The primary objective of this trial is to assess whether Rhodiola rosea improves fatigue when compared to placebo in nurses involved in shift work.
Study Started
Jan 31
Primary Completion
Apr 30
Study Completion
Apr 30
Last Update
Feb 15

Dietary Supplement Rhodiola rosea

1 capsule = 182 mg Rhodiola rosea extract standardized to 2.8% total rosavins. Take 2 capsules at start of wakeful period each day. Participants will self-determine need for second dose, of 1 capsule, within 4 hours of the initial dose.

  • Other names: University of Alberta Lot Number 120910


Inclusion Criteria:

Fourth year nursing students enrolled in NURS 495 (Nursing Practice)
Participating in permanent overnight (between 11 pm and 7 am) or rotating shift work
otherwise healthy
consent to participate in the study

Exclusion Criteria:

nurses aged 18 years or younger
breastfeeding or pregnant women, as confirmed by a blood test
female participants with child bearing potential not practicing a form of birth control throughout the trial
presence of a primary medical condition associated with fatigue (e.g. cardiac, gastrointestinal, respiratory, renal, rheumatologic, or oncologic disease)
presence of schizophrenia, bipolar disorder, dementia, eating disorders, insomnia or substance abuse
presence of diabetes
concurrent utilization of hypoglycaemic or agents for raising or lowering blood pressure
known allergy or hypersensitivity to Rhodiola rosea or Sedum family extracts or pollen
know allergy to microcrystalline cellulose or silicone dioxide
concurrent utilization of stimulant drug such as methylphenidate (Ritalin), amphetamine (Dexedrine, Adderall), methamphetamine (Desoxyn) and pemoline (Cylert)
concurrent utilization of other rhodiola or ginseng products (both fall in the same therapeutic category known as an "adaptogen")
any significant medical condition
any neurological or mental health condition
taking medication that has central nervous system effects
aged 55 years or older
low blood pressure or history of significant dizziness
No Results Posted