Single and Multiple Ascending Dose Safety Study of XPF-001 in Healthy Volunteers
Phase 1, Placebo-Controlled Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Oral Doses of XPF-001 and to Investigate the Effect of Food on the Pharmacokinetics of a Single Dose of XPF-001 in Healthy Subjects
The purpose of this study is to assess the safety, tolerability and pharmacokinetics of single and multiple doses of XPF-001 in healthy volunteers.
The effect of food on the pharmacokinetics of XPF-001 will also be studied.
Inclusion Criteria: Healthy subjects (Females of non-childbearing potential) with normal or clinically insignificant laboratory results, ECGs and physical examinations. Exclusion Criteria: Subjects with a presence or history of any clinically significant disease. Subjects who have participated in and investigational drug trial within 60 days of admission. Subjects who have used tobacco or nictoine products in the 1 month prior to admission Females who are pregnant or breastfeeding