Official Title

Effects of Sea Buckthorn Oil on Dry Eye
  • Phase

  • Study Type

  • Status

    Completed No Results Posted
  • Intervention/Treatment

    prulifloxacin ...
  • Study Participants

The objective is to study the effect of sea buckthorn oil on dry eye.
The objective is to study whether regular consumption of sea buckthorn berry oil can relieve the symptoms of dry eye syndrome. The study design is a parallel randomized double-blind placebo controlled trial. The participants daily consume sea buckthorn or placebo oil for 3 months. The dry eye symptoms will be monitored during the study using a validated questionnaire. In addition clinical dry eye tests are made by an ophthalmologist three time during the study. Samples will be taken for tear film lipid and cytokine analyses. Blood samples for the analyses of inflammatory markers are also obtained. The cytokine and other inflammation marker analyses are optional. The symptoms will be monitored and clinical tests made also 4 weeks after the participants have stopped consuming the study oils.
Study Started
Sep 30
Primary Completion
Mar 31
Study Completion
Mar 31
Last Update
Mar 20

Dietary Supplement Sea buckthorn (Hippophaë rhamnoides) oil

Dosage 2 g/d, frequency twice/d, duration 3 months

Dietary Supplement Placebo comparison

Placebo comparison, dosage 2 g/d, frequency twice/d, duration 3 months

SB Experimental

Sea buckthorn oil group

PL Placebo Comparator

Placebo group


Inclusion Criteria:

Dry eye symptoms

Exclusion Criteria:

Severe illness
Anticholinergic drugs
No Results Posted