Trial | NCT00693199  Report issue

Title

Effect of Amlodipine Monotherapy or Combined With Terazosin on Lower Urinary Tract Symptoms and Hypertension

  • Phase

    N/A

  • Study Type

    Interventional

  • Status

    Completed No Results Posted

  • Intervention/Treatment

    amlodipine terazosin ...

  • Study Participants

    360
The aim of this study was to investigate the efficacy and safety of low dose amlodipine alone, or combined with low dose terazosin in male patients with both lower urinary tract symptoms and hypertension.
Study Started
Jul 31
2006
Primary Completion
Oct 31
2006
Study Completion
Oct 31
2006
Last Update
Aug 08
2008
Estimate

Drug amlodipine

amlodipine 5mg once daily for 28 days

Drug terazosin

terazosin 2 mg once daily for 28 days

Drug amlodipine plus terazosin

amlodipine 5 mg plus terazosin 2 mg once daily for 28days

1 Experimental

2 Active Comparator

3 Experimental

Criteria 

Inclusion Criteria:

Men 50 years or older
with LUTS [defined as International Prostate Symptom Score (IPSS) >= 10].
Stage 1 or 2 essential hypertension (SBP >= 140 mm Hg and < 180 mm Hg and/or DBP >= 90 mm Hg and < 110 mm Hg)

Exclusion Criteria:

A history of postural hypotension
Secondary hypertension
Prostate cancer
Prostate surgery or other intervention
Use of any agents to influence the LUTS symptoms in the last 4 weeks
Other severe diseases
No Results Posted