Trial | NCT00526006  Report issue

Title

PPI-Rebound-Trial. A Study of the Clinical Relevance of the Acid Rebound Phenomena

  • Phase

    Phase 4

  • Study Type

    Interventional

  • Status

    Unknown status

  • Study Participants

    None
The acid secretion in the stomach seems to increase after withdrawal of min. 8 wks of treatment with a PPI (protonpump inhibitor) It is unknown if this acid rebound phenomenon is of clinical significance. In a doubleblinded and placebocontrolled study healthy volunteers are randomized to treatment with placebo or PPI + placebo. Gastrointestinal symptoms are scored once a week and.
Study Started
Sep 30
2007
Study Completion
Mar 31
2008
Anticipated
Last Update
Sep 06
2007
Estimate

Drug esomeprazole

40 mg od for 8 wks

Criteria 

Inclusion Criteria:

18 years +

Exclusion Criteria:

Dyspepsia, heartburn og acid regurgitation within the preceeding 4 weeks
Previous treatment with PPI og H2RA
Previous contact to doctor or hospital because of dyspepsia or reflux
Pregnancy or breast feeding
No Results Posted