Renoprotective Effect of Nisoldipine and Lisinopril in Type 1 Diabetic Nephropathy
Lead SponsorSteno Diabetes Center Copenhagen
StatusCompleted No Results Posted
Intervention/Treatmentnisoldipine lisinopril ...
The aim of the study was to compare the renoprotective effect of a long acting calcium antagonist (nisoldipine) with an angiotensin converting enzyme inhibitor (lisinopril)in type 1 diabetic patients with diabetic kidney disease. In total, 51 patients were randomised to treatment with one of these drugs for 4 years. Changes in kidney function, blood pressure and urinary excretion of albumin were measured every 6 months
Inclusion Criteria: diabetic nephropathy, type 1 diabetes, hypertension Exclusion Criteria: child bearing potential, non-diabetic kidney disease, malignancy