Organization Overview
Historical Acquisition Tree
Alternative names
Key: Amgen (19) Acquired (5)
adalimumab (humira) (2016)
anakinra (Kineret) (2001 NDA)
apremilast (otezla) (2014)
bevacizumab (avastin) (2017)
blinatumomab (blincyto) (2014 NDA)
cinacalcet (sensipar) (2004 NDA)
darbepoetin alfa (aranesp) (2001 NDA)
denosumab (prolia) (2010 NDA)
epoetin (Epogen) (1989)
erenumab (aimovig) (2018 NDA)
etelcalcetide (parsabiv) (2017 NDA)
evolocumab (repatha) (2015 NDA)
Filgrastim (neupogen) (1991 NDA)
infliximab (remicade) (2019)
ivabradine (corlanor) (2015 NDA)
palifermin (Kepivance) (2004 NDA)
panitumumab (vectibix) (2006 NDA)
rituximab (rituxan) (2020)
romiplostim (nplate) (2008 NDA)
romosozumab (Evenity) (2019 NDA)
sargramostim (leukine) (1991)
sotorasib (LUMAKRAS) (2021)
talimogene laherparepvec (Imlygic) (2015 NDA)
trastuzumab (herceptin) (2019)
Key: Amgen (20) Acquired (15)
blinatumomab (blincyto) (40 trials)
carfilzomib (kyprolis) (88 trials)
cinacalcet (sensipar) (34 trials)
darbepoetin alfa (aranesp) (76 trials)
denosumab (prolia) (81 trials)
diphtheria, tetanus and whole cell pertussis vaccine (Boostrix) (1 trial)
erenumab (aimovig) (25 trials)
etanercept (enbrel) (74 trials)
evolocumab (repatha) (55 trials)
Filgrastim (neupogen) (37 trials)
glycerol phenylbutyrate (ravicti) (3 trials)
hydroxychloroquine (plaquenil) (2 trials)
inactivated influenza vaccine (2 trials)
Key: Amgen (58) Acquired (31)
adalimumab (humira) (4 trials)
aflibercept (zaltrap) (1 trial)
alendronic acid (fosamax) (12 trials)
anastrozole (arimidex) (2 trials)
apremilast (otezla) (6 trials)
atorvastatin (lipitor) (8 trials)
autologous mononuclear stem cell (5 trials)
azathioprine (imuran) (1 trial)
betamethasone (celestone) (1 trial)
bevacizumab (avastin) (20 trials)
bortezomib (velcade) (5 trials)
brodalumab (siliq) (20 trials)
calcitriol (rocaltrol) (1 trial)
capecitabine (xeloda) (14 trials)
cisplatin (platinol) (29 trials)
clobetasol (dermovate) (2 trials)
cyclophosphamide (cytoxan) (47 trials)
daratumumab (darzalex) (5 trials)
docetaxel (taxotere) (23 trials)
doxorubicin (Doxil) (30 trials)
eculizumab (Soliris) (1 trial)
enoxaparin (lovenox) (1 trial)
epidermal growth factor (1 trial)
epirubicin (ellence) (16 trials)
etelcalcetide (parsabiv) (16 trials)
etoposide (vepesid) (12 trials)
ferric carboxymaltose (Injectafer) (1 trial)
fluorouracil (efudex) (46 trials)
gemcitabine (gemzar) (15 trials)
ibandronate (boniva) (1 trial)
infliximab (remicade) (1 trial)
irinotecan (Camptosar) (31 trials)
Isatuximab (Sarclisa) (2 trials)
lanadelumab (takhzyro) (1 trial)
melphalan (alkeran) (7 trials)
niclosamide (nicloside) (1 trial)
omecamtiv mecarbil (10 trials)
oxaliplatin (eloxatin) (29 trials)
paclitaxel (taxol) (45 trials)
palifermin (Kepivance) (12 trials)
pembrolizumab (keytruda) (16 trials)
pertuzumab (perjeta) (5 trials)
regorafenib (stivarga) (2 trials)
rimabotulinumtoxinB (Myobloc) (1 trial)
risedronate (actonel) (2 trials)
rituximab (rituxan) (21 trials)
romosozumab (Evenity) (21 trials)
sorafenib (nexavar) (30 trials)
sotorasib (LUMAKRAS) (27 trials)
sucroferric oxyhydroxide (Venofer) (1 trial)
tacrolimus (prograf) (2 trials)
talimogene laherparepvec (Imlygic) (33 trials)
tezepelumab (Tezspire) (21 trials)
thalidomide (Thalomid) (3 trials)
trastuzumab (herceptin) (13 trials)
trifluridine (viroptic) (2 trials)
ustekinumab (stelara) (4 trials)
vardenafil (levitra) (1 trial)
vinorelbine (navelbine) (6 trials)
Key: Amgen (91) Acquired (32)
allogeneic lymphocytes (1 trial)
allogeneic stem cells (2 trials)
Anti-thymocyte Globulin (Rabbit) (Thymoglobulin) (3 trials)
autologous hematopoietic stem cells (3 trials)
azacitidine (vidaza) (4 trials)
belantamab mafodotin (TECVAYLI) (1 trial)
belatacept (nujolix) (1 trial)
bendamustine (treanda) (3 trials)
clarithromycin (biaxin) (1 trial)
cobimetinib (cotellic) (1 trial)
cyclosporine (sandimmune) (2 trials)
cytarabine (cytosar-u) (10 trials)
dabrafenib (tafinlar) (2 trials)
dacarbazine (dtic-dome) (2 trials)
dapagliflozin (farxiga) (1 trial)
daunorubicin (cerubidine) (2 trials)
decitabine (dacogen) (2 trials)
doxycycline (vibramycin) (2 trials)
elotuzumab (empliciti) (2 trials)
erlotinib (tarceva) (3 trials)
everolimus (zortress) (3 trials)
exemestane (aromasin) (2 trials)
fludarabine (fludara) (2 trials)
fulvestrant (faslodex) (2 trials)
hemopoietic stem cell (2 trials)
ipilimumab (yervoy) (2 trials)
iron dextran (Imferon) (1 trial)
ixabepilone (ixempra) (1 trial)
lidocaine (xylocaine) (1 trial)
loratadine (claritin) (2 trials)
mercaptopurine (purinethol) (3 trials)
methylprednisolone (medrol) (2 trials)
metreleptin (myalept) (4 trials)
mitomycin (mutamycin) (1 trial)
mitoxantrone (novantrone) (4 trials)
mycophenolate (CellCept) (1 trial)
ofatumumab (arzerra) (1 trial)
pemetrexed (alimta) (3 trials)
pioglitazone (actos) (1 trial)
pomalidomide (pomalyst) (6 trials)
romidepsin (istodax) (2 trials)
ruxolitinib (jakafi) (1 trial)
sitagliptin (januvia) (1 trial)
soluble il-4 receptor (1 trial)
temozolomide (temodar) (1 trial)
topotecan (hycamtin) (2 trials)
trametinib (mekinist) (4 trials)
vemurafenib (zelboraf) (1 trial)
venetoclax (venclexta) (2 trials)
vinblastine (velban) (2 trials)
vincristine (oncovin) (11 trials)
vindesine (Eldisine) (2 trials)
Key: Amgen (76) Acquired (14)
atezolizumab (Tecentriq) (3 trials)
durvalumab (imfinzi) (1 trial)
enzalutamide (xtandi) (1 trial)
itraconazole (sporanox) (1 trial)
liraglutide (victoza) (1 trial)
Key: Amgen (3) Acquired (1)
Acquired Immunodeficiency Syndrome (Phase 2)
Acute Coronary Syndrome (Phase 3)
Adenocarcinoma (Phase 3)
Adenocarcinoma, Mucinous (Phase 2)
Adenocarcinoma of Lung (Phase 2)
Adenoma (Phase 2)
Adenoma, Islet Cell (Phase 2)
Adenoma, Pleomorphic (Phase 2)
Aggression (Phase 3)
AIDS-Related Complex (Phase 1)
Alzheimer Disease (Phase 3)
Amenorrhea (Phase 2)
Amyloidosis (Phase 1)
Anemia (Phase 4)
Anemia, Aplastic (Phase 2)
Angina Pectoris (Phase 2)
Angina, Stable (Phase 2)
Anorexia (Phase 1)
Anorexia Nervosa (Phase 1)
Anus Neoplasms (Phase 2)
Arthritis (Phase 4)
Arthritis, Juvenile (Phase 4)
Arthritis, Psoriatic (Phase 4)
Arthritis, Rheumatoid (Phase 4)
Asthma (Phase 3)
Astrocytoma (Phase 1)
Atherosclerosis (Phase 4)
Autonomic Nervous System Diseases (Phase 2)
Behcet Syndrome (Phase 3)
Biliary Tract Neoplasms (Phase 2)
Blast Crisis (Phase 2)
Bone Cysts (Phase 2)
Bone Cysts, Aneurysmal (Phase 2)
Bone Diseases (Phase 4)
Bone Diseases, Metabolic (Phase 3)
Bone Marrow Diseases (Phase 3)
Bone Neoplasms (Phase 4)
Brain Concussion (Phase 2)
Brain Injuries (Phase 2)
Brain Injuries, Traumatic (Phase 2)
Breast Neoplasms (Phase 3)
Bronchial Diseases (Phase 2)
Burkitt Lymphoma (Phase 2)
Calcinosis (Phase 4)
Carcinoid Tumor (Phase 2)
Carcinoma (Phase 3)
Carcinoma, Ductal (Phase 2)
Carcinoma, Ductal, Breast (Phase 3)
Carcinoma, Hepatocellular (Phase 2)
Carcinoma, Merkel Cell (Phase 2)
Carcinoma, Neuroendocrine (Phase 2)
Carcinoma, Non-Small-Cell Lung (Phase 4)
Carcinoma, Ovarian Epithelial (Phase 3)
Carcinoma, Renal Cell (Phase 3)
Carcinoma, Squamous Cell (Phase 3)
Carcinoma, Transitional Cell (Phase 2)
Cardiovascular Diseases (Phase 4)
Carotid Stenosis (Phase 4)
Cataract (Phase 3)
Chondroblastoma (Phase 2)
Chronic Pain (Phase 1)
Colitis (Phase 2)
Colitis, Ulcerative (Phase 2)
Colonic Neoplasms (Phase 3)
Colorectal Neoplasms (Phase 4)
Communicable Diseases (Phase 2)
Constriction, Pathologic (Phase 4)
Coronary Artery Disease (Phase 4)
Coronary Disease (Phase 3)
Crohn Disease (Phase 2)
Cystadenocarcinoma (Phase 2)
Deglutition Disorders (Phase 2)
Dermatitis (Phase 2)
Dermatitis, Atopic (Phase 2)
Dermatomyositis (Phase 1)
Desmoplastic Small Round Cell Tumor (Phase 2)
Diabetes Mellitus (Phase 4)
Diabetes Mellitus, Type 1 (Phase 2)
Diabetes Mellitus, Type 2 (Phase 3)
Disease (Phase 2)
Dyslipidemias (Phase 3)
Eczema (Phase 2)
Endocrine Gland Neoplasms (Phase 3)
Erectile Dysfunction (Phase 3)
Erythema (Phase 2)
Esophageal Neoplasms (Phase 2)
Esophageal Squamous Cell Carcinoma (Phase 3)
Exanthema (Phase 2)
Facial Pain (Phase 4)
Facies (Phase 4)
Fallopian Tube Neoplasms (Phase 3)
Feeding and Eating Disorders (Phase 1)
Fibroma (Phase 2)
Fractures, Bone (Phase 3)
Gallbladder Neoplasms (Phase 2)
Gastrointestinal Neoplasms (Phase 2)
Gastrointestinal Stromal Tumors (Phase 2)
Genital Neoplasms, Female (Phase 2)
Giant Cell Tumor of Bone (Phase 4)
Giant Cell Tumors (Phase 4)
Glioblastoma (Phase 2)
Glioma (Phase 2)
Gliosarcoma (Phase 2)
Glomerulonephritis (Phase 1)
Gout (Phase 4)
Graft vs Host Disease (Phase 2)
Granuloma (Phase 2)
Granuloma, Giant Cell (Phase 2)
Headache (Phase 4)
Headache Disorders, Secondary (Phase 4)
Head and Neck Neoplasms (Phase 3)
Heart Diseases (Phase 3)
Heart Failure (Phase 4)
Hemangiosarcoma (Phase 2)
Hematologic Diseases (Phase 2)
Hemoglobinuria (Phase 3)
Hemoglobinuria, Paroxysmal (Phase 3)
HIV Infections (Phase 3)
Hodgkin Disease (Phase 2)
Hot Flashes (Phase 2)
Hypercalcemia (Phase 3)
Hypercholesterolemia (Phase 4)
Hyperlipidemias (Phase 4)
Hyperlipoproteinemias (Phase 4)
Hyperlipoproteinemia Type II (Phase 4)
Hyperparathyroidism (Phase 4)
Hyperparathyroidism, Primary (Phase 4)
Hyperparathyroidism, Secondary (Phase 4)
Hyperphosphatemia (Phase 2)
Hypersensitivity (Phase 2)
Hypersensitivity, Immediate (Phase 2)
Hypophosphatemia (Phase 3)
Immune System Diseases (Phase 2)
Immunoblastic Lymphadenopathy (Phase 1)
Immunologic Deficiency Syndromes (Phase 1)
Infarction (Phase 3)
Infections (Phase 2)
Inflammation (Phase 3)
Inflammatory Breast Neoplasms (Phase 3)
Intestinal Neoplasms (Phase 1)
Intracranial Arteriosclerosis (Phase 4)
Ischemia (Phase 4)
Keratoacanthoma (Phase 2)
Kidney Diseases (Phase 4)
Kidney Failure, Chronic (Phase 4)
Kidney Neoplasms (Phase 2)
Leukemia (Phase 4)
Leukemia, Erythroblastic, Acute (Phase 1)
Leukemia, Lymphocytic, Chronic, B-Cell (Phase 2)
Leukemia, Lymphoid (Phase 4)
Leukemia-Lymphoma, Adult T-Cell (Phase 1)
Leukemia, Megakaryoblastic, Acute (Phase 1)
Leukemia, Monocytic, Acute (Phase 1)
Leukemia, Myeloid (Phase 2)
Leukemia, Myeloid, Accelerated Phase (Phase 2)
Leukemia, Myeloid, Acute (Phase 2)
Leukemia, Myelomonocytic, Acute (Phase 1)
Leukemia, Myelomonocytic, Juvenile (Phase 2)
Leukemia, Prolymphocytic (Phase 1)
Leukemia, T-Cell (Phase 1)
Lipodystrophy (Phase 2)
Liver Diseases (Phase 1)
Liver Neoplasms (Phase 2)
Lung Diseases (Phase 2)
Lung Diseases, Obstructive (Phase 2)
Lung Neoplasms (Phase 4)
Lupus Erythematosus, Cutaneous (Phase 1)
Lupus Erythematosus, Discoid (Phase 1)
Lupus Erythematosus, Systemic (Phase 2)
Lymphoma (Phase 3)
Lymphoma, B-Cell (Phase 3)
Lymphoma, Extranodal NK-T-Cell (Phase 1)
Lymphoma, Follicular (Phase 1)
Lymphoma, Large B-Cell, Diffuse (Phase 3)
Lymphoma, Large-Cell, Anaplastic (Phase 1)
Lymphoma, Mantle-Cell (Phase 2)
Lymphoma, Non-Hodgkin (Phase 3)
Lymphoma, T-Cell (Phase 2)
Lymphoma, T-Cell, Cutaneous (Phase 1)
Lymphoma, T-Cell, Peripheral (Phase 2)
Macular Degeneration (Phase 3)
Malignant Carcinoid Syndrome (Phase 2)
Melanoma (Phase 4)
Metabolic Syndrome (Phase 2)
Migraine Disorders (Phase 4)
Mucocutaneous Lymph Node Syndrome (Phase 2)
Mucositis (Phase 3)
Muir-Torre Syndrome (Phase 2)
Multiple Myeloma (Phase 4)
Mycoses (Phase 1)
Mycosis Fungoides (Phase 1)
Myelodysplastic Syndromes (Phase 3)
Myeloproliferative Disorders (Phase 2)
Myocardial Infarction (Phase 3)
Myocardial Ischemia (Phase 3)
Myositis (Phase 1)
Myositis, Inclusion Body (Phase 1)
Nasal Polyps (Phase 1)
Necrosis (Phase 3)
Neoplasm Metastasis (Phase 4)
Neoplasm, Residual (Phase 4)
Neoplasms (Phase 3)
Neoplasms, Plasma Cell (Phase 4)
Neoplasms, Second Primary (Phase 3)
Neoplasms, Squamous Cell (Phase 3)
Neoplastic Cells, Circulating (Phase 2)
Nephritis (Phase 1)
Neuroectodermal Tumors (Phase 2)
Neuroectodermal Tumors, Primitive (Phase 2)
Neuroendocrine Tumors (Phase 2)
Neutropenia (Phase 4)
Obesity (Phase 1)
Oral Ulcer (Phase 3)
Osteoarthritis (Phase 2)
Osteoarthritis, Knee (Phase 1)
Osteoblastoma (Phase 2)
Osteogenesis Imperfecta (Phase 3)
Osteoporosis (Phase 4)
Osteoporosis, Postmenopausal (Phase 4)
Ovarian Neoplasms (Phase 3)
Pancreatic Neoplasms (Phase 3)
Pancytopenia (Phase 1)
Paraneoplastic Syndromes (Phase 2)
Parathyroid Neoplasms (Phase 4)
Parkinson Disease (Phase 2)
Peripheral Arterial Disease (Phase 4)
Peripheral Vascular Diseases (Phase 4)
Peritoneal Neoplasms (Phase 3)
Philadelphia Chromosome (Phase 2)
Plaque, Atherosclerotic (Phase 4)
Pleural Effusion (Phase 2)
Pleural Effusion, Malignant (Phase 2)
Polyps (Phase 1)
Post-Concussion Syndrome (Phase 2)
Post-Traumatic Headache (Phase 2)
Preleukemia (Phase 3)
Primary Dysautonomias (Phase 2)
Prostatic Neoplasms (Phase 3)
Psoriasis (Phase 4)
Psychotic Disorders (Phase 1)
Pulmonary Disease, Chronic Obstructive (Phase 2)
Purpura (Phase 4)
Purpura, Thrombocytopenic (Phase 4)
Purpura, Thrombocytopenic, Idiopathic (Phase 4)
Rectal Neoplasms (Phase 2)
Recurrence (Phase 3)
Renal Insufficiency (Phase 4)
Renal Insufficiency, Chronic (Phase 4)
Respiratory Hypersensitivity (Phase 2)
Respiratory Tract Diseases (Phase 2)
Salivary Gland Neoplasms (Phase 2)
Sarcoma (Phase 2)
Sarcoma, Ewing (Phase 2)
Sarcoma, Kaposi (Phase 2)
Schizophrenia (Phase 2)
Scleroderma, Diffuse (Phase 1)
Scleroderma, Systemic (Phase 1)
Sclerosis (Phase 1)
Serotonin Syndrome (Phase 2)
Sezary Syndrome (Phase 1)
Shock (Phase 4)
Shock, Cardiogenic (Phase 4)
Sinusitis (Phase 1)
Sjogren's Syndrome (Phase 2)
Skin Neoplasms (Phase 4)
Small Cell Lung Carcinoma (Phase 3)
Smoldering Multiple Myeloma (Phase 2)
Spondylarthritis (Phase 2)
Spondylitis (Phase 3)
Spondylitis, Ankylosing (Phase 3)
Squamous Cell Carcinoma of Head and Neck (Phase 2)
Stomach Neoplasms (Phase 3)
Stomatitis (Phase 3)
Syndrome (Phase 3)
Syringoma (Phase 2)
Tachycardia (Phase 4)
Testicular Neoplasms (Phase 2)
Thrombocytopenia (Phase 4)
Thyroid Diseases (Phase 3)
Thyroid Neoplasms (Phase 3)
Triple Negative Breast Neoplasms (Phase 2)
Ulcer (Phase 2)
Ureteral Neoplasms (Phase 2)
Urinary Bladder Neoplasms (Phase 2)
Vascular Calcification (Phase 4)
Vascular Diseases (Phase 4)
Ventricular Dysfunction (Phase 3)
Ventricular Dysfunction, Left (Phase 2)
Vitiligo (Phase 2)
Waldenstrom Macroglobulinemia (Phase 3)