Organization | World Health Organization

World Health Organization Report issue

Government Phase 1 Phase 2 Phase 3 Phase 4

Founded: Geneva Switzerland (1948)

Organization Overview

First Clinical Trial

1993

NCT01019408

First Marketed Drug

None

First NDA Approval

None

Last Known Activity

2021

Timeline

NOW

Now

Alternative names

Initiative for Vaccine Research, World Health Organization | Per Ashorn | WHO Collaborating Center for Epidemiology and Preventive Dentistry | WHO, GBUI, Geneva, Switserland | WHO Pneumococcal Serology Reference Laboratory Institute of Child Health | World Health Organization | World Health Organization (WHO), R&D Blueprint, Geneva, Switzerland | World Heath Organization

Active Ingredients

Drugs in Phase 4 Trials (23)

albendazole (Albenza) (2 trials)

amodiaquine (camoquin) (5 trials)

artemether (3 trials)

artesunate (15 trials)

azithromycin (zithromax) (4 trials)

bivalent oral polio vaccine (bopv), type 1 and type 3 (5 trials)

chloroquine (5 trials)

coartem (4 trials)

dihydroqinghaosu (5 trials)

ivermectin (stromectol) (3 trials)

live oral poliovirus type 1, 2 and 3 (3 trials)

lumefantrine (Coartem) (7 trials)

mebendazole (vermox) (2 trials)

piperaquinoline (5 trials)

poliovirus vaccine inactivated (6 trials)

praziquantel (biltricide) (2 trials)

primaquine (4 trials)

procaine benzylpenicillin (novocaine) (10 trials)

pyrimethamine (daraprim) (11 trials)

remdesivir (2 trials)

sulfadoxine (10 trials)

Drugs in Phase 3 Trials (32)

acetylsalicylic acid (aspirin) (2 trials)

amphotericin b (fungizone) (1 trial)

bedaquiline (sirturo) (2 trials)

benznidazole (Rochagan) (1 trial)

citalopram (celexa) (1 trial)

clarithromycin (biaxin) (1 trial)

clofazimine (lamprene) (2 trials)

eflornithine (ornidyl) (1 trial)

estradiol (progynon depot) (1 trial)

gatifloxacin (Zymar) (1 trial)

gentamicin (garamycin) (1 trial)

inactivated influenza vaccine (6 trials)

ivacflu (2 trials)

linezolid (zyvox) (2 trials)

menafrivac (1 trial)

miltefosine (impavido) (2 trials)

moxidectin (3 trials)

moxifloxacin (avelox) (2 trials)

nifurtimox (1 trial)

paromomycin (humatin) (1 trial)

phosphate-buffered saline (2 trials)

pretomanid (2 trials)

ramipril (altace) (1 trial)

reboxetine (1 trial)

sertraline (zoloft) (1 trial)

simvastatin (zocor) (2 trials)

st 1435 (1 trial)

streptomycin (kabikinase) (1 trial)

tetanus toxoid (1 trial)

venlafaxine (effexor) (1 trial)

vitamin d3 (2 trials)

10 valent pneumococcal conjugate vaccine (1 trial)

Drugs in Phase 2 Trials (19)

benzathine penicillin (2 trials)

brimonidine (alphagan) (1 trial)

cad3-zebov (1 trial)

calcium (1 trial)

cefixime (suprax) (1 trial)

enalapril (vasotec) (1 trial)

hydrochlorothiazide (esidrix) (1 trial)

influenza vlp vaccine (1 trial)

latanoprost (xalatan) (1 trial)

lisinopril (zestril) (1 trial)

lopinavir (Kaletra) (1 trial)

mencevax (1 trial)

novel monovalent oral poliovirus vaccine type 2 (1 trial)

oseltamivir (tamiflu) (1 trial)

ritonavir (Norvir) (1 trial)

tivantinib (1 trial)

vaxigrip (1 trial)

vitamin a (4 trials)

vsv-zebov (2 trials)

Drugs in Phase 1 Trials (6)

live attenuated influenza virus vaccine (flumist) (1 trial)

montanide isa 720 (1 trial)

plasmodium falciparum chimeric prot. 2.9 (1 trial)

rvsvdelta-zebov-gp (1 trial)

tenofovir (viread) (2 trials)

zn2+ (5 trials)

Drugs in Other Trials (16)

artemisinin (1 trial)

ct0590 car t cells (1 trial)

dapsone (aczone) (1 trial)

doxycycline (vibramycin) (1 trial)

ferrous sulfate (1 trial)

folic acid (1 trial)

killed oral cholera vaccine (1 trial)

liraglutide (victoza) (2 trials)

medroxyprogesterone (provera) (1 trial)

mefloquine (lariam) (1 trial)

monovalent oral polio vaccines (mopv1) (2 trials)

norgestrel (Ovral) (1 trial)

quinine (qualaquin) (1 trial)

xylitol (1 trial)

zinc dichloride (2 trials)

Indications

Experimental Indications (Clinical Trials, Phases 1-4)

Avitaminosis (Phase 3)

Buruli Ulcer (Phase 3)

Cardiovascular Diseases (Phase 2)

Chagas Disease (Phase 3)

Communicable Diseases (Phase 4)

Diarrhea (Phase 3)

Elephantiasis (Phase 4)

Elephantiasis, Filarial (Phase 4)

Extensively Drug-Resistant Tuberculosis (Phase 3)

Filariasis (Phase 4)

Glaucoma (Phase 2)

Glaucoma, Open-Angle (Phase 2)

Glucosephosphate Dehydrogenase Deficiency (Phase 4)

Heart Diseases (Phase 3)

Hemorrhagic Fever, Ebola (Phase 2)

Hemorrhagic Fevers, Viral (Phase 1)

HIV Infections (Phase 1)

Infant, Newborn, Diseases (Phase 3)

Infarction (Phase 3)

Infections (Phase 4)

Influenza, Human (Phase 3)

Influenza in Birds (Phase 3)

Intestinal Diseases (Phase 4)

Intestinal Diseases, Parasitic (Phase 4)

Intestinal Volvulus (Phase 3)

Kidney Diseases (Phase 2)

Leishmaniasis (Phase 3)

Leishmaniasis, Cutaneous (Phase 3)

Leishmaniasis, Visceral (Phase 3)

Lipid Metabolism Disorders (Phase 2)

Malaria (Phase 4)

Malaria, Falciparum (Phase 4)

Malaria, Vivax (Phase 3)

Malnutrition (Phase 4)

Meningitis (Phase 3)

Meningitis, Meningococcal (Phase 2)

Metabolic Diseases (Phase 2)

Metabolic Syndrome (Phase 2)

Myocardial Infarction (Phase 3)

Nematode Infections (Phase 4)

Neonatal Sepsis (Phase 3)

Night Blindness (Phase 2)

Obesity, Abdominal (Phase 2)

Onchocerciasis (Phase 3)

Parasitemia (Phase 3)

Parasitic Diseases (Phase 4)

Pneumonia (Phase 4)

Poliomyelitis (Phase 4)

Pregnancy Complications (Phase 3)

Renal Insufficiency (Phase 2)

Renal Insufficiency, Chronic (Phase 2)

Rickets (Phase 3)

Schistosomiasis (Phase 4)

Schistosomiasis haematobia (Phase 3)

Schistosomiasis mansoni (Phase 4)

Sepsis (Phase 3)

Syphilis (Phase 2)

Toxemia (Phase 3)

Trypanosomiasis (Phase 3)

Trypanosomiasis, African (Phase 3)

Tuberculosis (Phase 3)

Tuberculosis, Multidrug-Resistant (Phase 3)

Tuberculosis, Pulmonary (Phase 3)

Virus Diseases (Phase 1)

Vitamin A Deficiency (Phase 2)

Vitamin D Deficiency (Phase 3)

Yaws (Phase 4)

Overview

Highest Phase: Phase 4
# of Trials: 134
# of Trial APIs: 96