Organization Overview
Historical Acquisition Tree
Alternative names
Key: Bayer (68) Acquired (1)
acarbose (precose) (1995 NDA)
acetic acid (vosol) (1966)
acetylsalicylic acid (aspirin) (1965 NDA)
alcaftadine (Lastacaft) (2010)
aluminum acetate (dome burow) (1976)
aprotinin (trasylol) (1993 NDA)
avobenzone (shade uvaguard) (1992)
azelastine (astelin) (2021)
azlocillin (azlin) (1982 NDA)
butenafine (mentax) (2001)
butoconazole (Femstat) (1995)
cerivastatin (baycol) (1997 NDA)
chloroquine (NDA)
ciprofloxacin (cipro) (1987 NDA)
clioquinol (nystaform) (NDA)
copanlisib (aliqopa) (2017 NDA)
cyanocobalamin (berocca) (1949)
dacarbazine (dtic-dome) (1975 NDA)
darolutamide (Nubeqa) (2019 NDA)
dexchlorpheniramine maleate (polaramine) (1950)
diatrazoate meglumine (Renografin) (1982)
dienogest (natazia) (2010 NDA)
diphenhydramine (benadryl) (2014)
drospirenone (Yasmin) (NDA)
estradiol (progynon depot) (1994)
ethinyl estradiol (Estinyl) (1998)
finerenone (2021)
gadobutrol (gadavist) (2011 NDA)
gadopenteate dimeglumine (magnevist) (1988 NDA)
gadoxetate disodium (eovist) (2008 NDA)
insulin human (humulin) (1988)
interferon beta-1b (betaseron) (1993)
iopromide (ultravist ) (1995)
ketoprofen (orudis) (1995)
larotrectinib (vitrakvi) (2018)
lepirudin (refludan) (1998 NDA)
levomefolate calcium (Methofoline) (2010 NDA)
lithium (lithonate) (1985)
loratadine (claritin) (1993)
mezlocillin (mezlin) (1981 NDA)
moxifloxacin (avelox) (1999 NDA)
naproxen (naprosyn) (1994)
neomycin (1964)
nifedipine (procardia) (1985)
nifurtimox (2020)
nimodipine (nimotop) (1988 NDA)
norgestrel (Ovral) (1998)
octinoxate (1992)
omeprazole (prilosec) (2009)
oxybenzone (1992)
oxymetazoline (ocuclear) (1986)
piperonyl butoxide (Rid Mousse) (2000)
polyethylene glycol 3350 (colyte) (2006)
praziquantel (biltricide) (1982 NDA)
prednisone (meticorten) (1972)
pseudoephedrine (Benylin) (1981)
pyrethrins (rid mousse) (2000)
quinidine (1969)
radium-223 (xofigo) (2013 NDA)
regorafenib (stivarga) (2012 NDA)
riociguat (adempas) (2013 NDA)
rivaroxaban (xarelto) (2002)
sodium bicarbonate (2009)
sodium iopodate (1982)
sorafenib (nexavar) (2005 NDA)
sulfameter (sulla) (1966 NDA)
urea (1976)
vardenafil (levitra) (2003 NDA)
vitamin a (1973)
Key: Bayer (116) Acquired (2)
abiraterone (zytiga) (5 trials)
acarbose (precose) (21 trials)
acetaminophen (tylenol) (9 trials)
acetylsalicylic acid (aspirin) (52 trials)
adapalene (differin) (1 trial)
aflibercept (zaltrap) (64 trials)
alemtuzumab (campath) (30 trials)
aluminum hydroxide (Gaviscon) (2 trials)
amlodipine (norvasc) (2 trials)
antihemophilic factor viii human (Hemofil M) (23 trials)
antihemophilic factor viii (Recombinant) (Adynovate) (12 trials)
azelaic acid (azelex) (19 trials)
azelastine (astelin) (2 trials)
brimonidine (alphagan) (2 trials)
ceftriaxone (rocephin) (4 trials)
ciprofloxacin (cipro) (24 trials)
clavulanate (Augmentin) (7 trials)
clopidogrel (plavix) (8 trials)
darifenacin (enablex) (3 trials)
dexmedetomidine (precedex) (2 trials)
diphenhydramine (benadryl) (7 trials)
doxycycline (vibramycin) (2 trials)
drospirenone (Yasmin) (57 trials)
enzalutamide (xtandi) (9 trials)
estradiol (progynon depot) (38 trials)
ethinyl estradiol (Estinyl) (75 trials)
fexofenadine (allegra) (1 trial)
fluconazole (diflucan) (2 trials)
fluticasone (cutivate) (1 trial)
gadobenate (multihance) (1 trial)
gadobutrol (gadavist) (26 trials)
gadodiamide (omniscan) (1 trial)
gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (1 trial)
gadopenteate dimeglumine (magnevist) (14 trials)
gadoteric acid (Dotarem) (3 trials)
gadoteridol (prohance) (3 trials)
gadoxetate disodium (eovist) (9 trials)
gemcitabine (gemzar) (16 trials)
hydrocodone (hycodan) (1 trial)
icosapent ethyl (vascepa) (1 trial)
iloprost (ventavis) (18 trials)
immune globulin (human) (2 trials)
insulin glargine (toujeo) (1 trial)
insulin human (humulin) (2 trials)
iodixanol (visipaque) (1 trial)
iopromide (ultravist ) (7 trials)
levofloxacin (levaquin) (4 trials)
lidocaine (xylocaine) (2 trials)
lisinopril (zestril) (1 trial)
loratadine (claritin) (9 trials)
medroxyprogesterone (provera) (2 trials)
mefenamic acid (ponstel) (1 trial)
methylprednisolone (medrol) (3 trials)
metronidazole (flagyl) (6 trials)
misoprostol (cytotec) (1 trial)
moxifloxacin (avelox) (40 trials)
naproxen (naprosyn) (25 trials)
nateglinide (starlix) (1 trial)
nifedipine (procardia) (24 trials)
norgestrel (Ovral) (56 trials)
omeprazole (prilosec) (7 trials)
phenprocoumon (liquamar) (7 trials)
pimecrolimus (elidel) (1 trial)
prednisone (meticorten) (16 trials)
procaine benzylpenicillin (novocaine) (9 trials)
pseudoephedrine (Benylin) (5 trials)
radium-223 (xofigo) (51 trials)
regorafenib (stivarga) (91 trials)
riociguat (adempas) (39 trials)
rivaroxaban (xarelto) (122 trials)
rurioctocog alfa pegol (2 trials)
sildenafil (viagra) (5 trials)
sitagliptin (januvia) (6 trials)
sorafenib (nexavar) (189 trials)
tacrolimus (prograf) (2 trials)
telmisartan (micardis) (14 trials)
testosterone (delatestryl) (15 trials)
tranexamic acid (cyklokapron) (4 trials)
vardenafil (levitra) (54 trials)
Key: Bayer (100) Acquired (4)
adenosine (Adenocard) (1 trial)
Anti-thymocyte Globulin (Rabbit) (Thymoglobulin) (1 trial)
aprotinin (trasylol) (5 trials)
avobenzone (shade uvaguard) (3 trials)
azithromycin (zithromax) (1 trial)
bendamustine (treanda) (2 trials)
butenafine (mentax) (4 trials)
candesartan (atacand) (6 trials)
capecitabine (xeloda) (7 trials)
carboplatin (paraplatin) (14 trials)
cisplatin (platinol) (17 trials)
clarithromycin (biaxin) (2 trials)
coagulation factor viia (recombinant) (NovoSevenRT) (1 trial)
copanlisib (aliqopa) (35 trials)
cyclophosphamide (cytoxan) (20 trials)
darbepoetin alfa (aranesp) (5 trials)
darolutamide (Nubeqa) (24 trials)
deoxycholic acid (kybella) (2 trials)
desogestrel (Mercilon) (10 trials)
diltiazem (cardizem) (1 trial)
docetaxel (taxotere) (10 trials)
doxorubicin (Doxil) (13 trials)
enoxaparin (lovenox) (20 trials)
erlotinib (tarceva) (7 trials)
ethambutol (myambutol) (2 trials)
fludarabine (fludara) (13 trials)
fondaparinux sodium (arixtra) (3 trials)
gadofosveset trisodium (ablavar) (1 trial)
glatiramer acetate (copaxone) (1 trial)
heparin (liquaemin) (5 trials)
ibritumomab tiuxetan (zevalin) (13 trials)
idarubicin (idamycin) (2 trials)
isoniazid (nydrazid) (3 trials)
lansoprazole (prevacid) (1 trial)
metformin (glucophage) (3 trials)
n5-methyltetrahydropteroylglutamate (1 trial)
nivolumab (opdivo) (10 trials)
norelgestromin (Evra) (2 trials)
oxybutynin (ditropan) (1 trial)
paclitaxel (taxol) (16 trials)
pantoprazole (protonix) (1 trial)
phenylbenzimidazolesulfonic acid (1 trial)
phenylephrine (Prefrin) (6 trials)
piperacillin (pipracil) (2 trials)
prasterone (intrarosa) (1 trial)
ranibizumab (lucentis) (6 trials)
rituximab (rituxan) (22 trials)
sargramostim (leukine) (24 trials)
sodium lauryl sulfate (1 trial)
tedizolid phosphate (sivextro) (3 trials)
ticagrelor (brilinta) (3 trials)
trifluridine (viroptic) (1 trial)
vincristine (oncovin) (8 trials)
Key: Bayer (159) Acquired (4)
adrenomedullin (22-52) (1 trial)
aldesleukin (proleukin) (3 trials)
allogeneic adipose derived mesenchymal stem cell (1 trial)
allogeneic stem cells (1 trial)
anastrozole (arimidex) (2 trials)
anetumab ravtansine (9 trials)
atezolizumab (tecentriq) (2 trials)
azacitidine (vidaza) (2 trials)
bevacizumab (avastin) (4 trials)
bicalutamide (casodex) (3 trials)
bisacodyl (Halflytely) (1 trial)
cabazitaxel (jevtana kit) (1 trial)
celecoxib (celebrex) (1 trial)
cetuximab (erbitux) (3 trials)
cobimetinib (cotellic) (2 trials)
crizotinib (xalkori) (1 trial)
cyclosporine (sandimmune) (2 trials)
dabrafenib (tafinlar) (1 trial)
dacarbazine (dtic-dome) (3 trials)
dapagliflozin (farxiga) (1 trial)
degarelix acetate (firmagon) (1 trial)
dehydroepiandrosterone (1 trial)
desvenlafaxine (pristiq) (1 trial)
dexchlorpheniramine maleate (polaramine) (1 trial)
dexpanthenol (Berocca) (5 trials)
epirubicin (ellence) (1 trial)
eplerenone (inspra) (3 trials)
escitalopram (lexapro) (1 trial)
etoposide (vepesid) (5 trials)
everolimus (zortress) (5 trials)
exemestane (aromasin) (1 trial)
filgrastim (neupogen) (2 trials)
florbetaben F-18 (neuraceq) (4 trials)
Fluciclovine (Axumin) (1 trial)
fludeoxyglucose f-18 (2 trials)
fluocinonide (lidex) (1 trial)
fulvestrant (faslodex) (3 trials)
gadoversetamide (optimark) (1 trial)
ibrutinib (imbruvica) (2 trials)
interferon gamma-1b (actimmune) (1 trial)
ixabepilone (ixempra) (1 trial)
ketoconazole (nizoral) (3 trials)
leuprolide (lupron) (2 trials)
melphalan (alkeran) (2 trials)
methoxy polyethylene glycol-epoetin beta (Mircera) (2 trials)
midazolam (versed) (10 trials)
mitoxantrone (novantrone) (5 trials)
mycophenolate (myfortic) (2 trials)
neladenoson bialanate (4 trials)
niclosamide (nicloside) (2 trials)
olaparib (lynparza) (2 trials)
oxaliplatin (eloxatin) (6 trials)
palbociclib (ibrance) (2 trials)
panitumumab (vectibix) (1 trial)
pembrolizumab (keytruda) (7 trials)
pemetrexed (alimta) (3 trials)
pneumococcal 13-valent conjugate vaccine (prevnar 13) (1 trial)
polyethylene glycol 3350 (colyte) (1 trial)
spironolactone (aldactone) (1 trial)
tamoxifen (nolvadex) (1 trial)
tazarotene (tazorac) (2 trials)
temozolomide (temodar) (7 trials)
temsirolimus (torisel) (1 trial)
terbinafine (lamisil) (1 trial)
thalidomide (Thalomid) (1 trial)
topotecan (hycamtin) (3 trials)
trametinib (mekinist) (1 trial)
trastuzumab (herceptin) (3 trials)
vemurafenib (zelboraf) (3 trials)
venetoclax (venclexta) (1 trial)
venlafaxine (effexor) (1 trial)
vinblastine (velban) (1 trial)
vinorelbine (navelbine) (2 trials)
vismodegib (erivedge) (2 trials)
Key: Bayer (99) Acquired (4)
18f-fluoromethyltyrosine (2 trials)
allogeneic natural killer cells (1 trial)
betamethasone (celestone) (2 trials)
calcipotriene (dovonex) (2 trials)
clindamycin (cleocin) (1 trial)
clobetasol (dermovate) (3 trials)
clofarabine (clolar) (1 trial)
cobicistat (stribild) (1 trial)
darunavir (prezista) (1 trial)
dolutegravir (tivicay) (1 trial)
durvalumab (imfinzi) (1 trial)
elvitegravir (vitekta) (1 trial)
emtricitabine (emtriva) (1 trial)
erythromycin (ilosone) (1 trial)
esomeprazole (nexium) (1 trial)
human factor ix complex (prothrombin complex concentrate) (Kcentra) (2 trials)
hypericum perforatum (1 trial)
indinavir (crixivan) (1 trial)
isosorbide (isordil) (1 trial)
itraconazole (sporanox) (8 trials)
miconazole (monistat) (2 trials)
nimodipine (nimotop) (1 trial)
nitroglycerin (transderm-nitro) (2 trials)
nonoxynol-9 (Delfen) (1 trial)
pazopanib (votrient) (1 trial)
plerixafor (mozobil) (1 trial)
prednicarbate (dermatop) (1 trial)
romidepsin (istodax) (1 trial)
rosuvastatin (crestor) (4 trials)
saquinavir (invirase) (1 trial)
sirolimus (rapamune) (2 trials)
Abdominal Abscess (Phase 3)
Abscess (Phase 4)
Acalculous Cholecystitis (Phase 3)
Acne Vulgaris (Phase 4)
Acquired Immunodeficiency Syndrome (Phase 2)
Acute Coronary Syndrome (Phase 4)
Acute Disease (Phase 4)
Acute Lung Injury (Phase 2)
Acute Pain (Phase 4)
Adenocarcinoma (Phase 2)
Adenocarcinoma of Lung (Phase 2)
Altitude Sickness (Phase 4)
Alzheimer Disease (Phase 2)
Amyloidosis (Phase 2)
Anemia (Phase 3)
Anemia, Aplastic (Phase 2)
Anemia, Sickle Cell (Phase 2)
Angina Pectoris (Phase 2)
Angina, Stable (Phase 2)
Angina, Unstable (Phase 3)
Antiphospholipid Syndrome (Phase 4)
Aortic Valve Stenosis (Phase 3)
Apnea (Phase 2)
Arthritis, Rheumatoid (Phase 1)
Astrocytoma (Phase 2)
Atherosclerosis (Phase 4)
Atrial Fibrillation (Phase 4)
Atrial Flutter (Phase 3)
Back Pain (Phase 3)
Bacterial Infections (Phase 4)
Bile Duct Neoplasms (Phase 2)
Biliary Tract Neoplasms (Phase 2)
Blood Coagulation Disorders (Phase 3)
Blood Loss, Surgical (Phase 3)
Bone Diseases (Phase 4)
Bone Diseases, Metabolic (Phase 4)
Bone Marrow Diseases (Phase 2)
Bone Neoplasms (Phase 2)
Brain Diseases (Phase 2)
Brain Neoplasms (Phase 3)
Breast Neoplasms (Phase 3)
Bronchiectasis (Phase 3)
Bronchitis (Phase 4)
Bronchitis, Chronic (Phase 4)
Calcinosis (Phase 4)
Candidiasis (Phase 4)
Candidiasis, Vulvovaginal (Phase 4)
Carcinoid Tumor (Phase 1)
Carcinoma (Phase 4)
Carcinoma, Adenoid Cystic (Phase 2)
Carcinoma, Ductal (Phase 2)
Carcinoma, Hepatocellular (Phase 4)
Carcinoma, Non-Small-Cell Lung (Phase 3)
Carcinoma, Ovarian Epithelial (Phase 2)
Carcinoma, Renal Cell (Phase 4)
Carcinoma, Small Cell (Phase 2)
Carcinoma, Squamous Cell (Phase 2)
Carcinoma, Transitional Cell (Phase 3)
Cardiomyopathies (Phase 2)
Cardiovascular Abnormalities (Phase 3)
Cardiovascular Diseases (Phase 4)
Carotid Stenosis (Phase 3)
Cellulitis (Phase 2)
Central Nervous System Diseases (Phase 3)
Central Nervous System Neoplasms (Phase 2)
Cerebral Infarction (Phase 2)
Chagas Disease (Phase 3)
Cholangiocarcinoma (Phase 2)
Cholecystitis (Phase 3)
Cholecystitis, Acute (Phase 3)
Cholera (Phase 3)
Choroidal Neovascularization (Phase 3)
Cognitive Dysfunction (Phase 1)
Colitis (Phase 2)
Colitis, Ulcerative (Phase 2)
Collagen Diseases (Phase 3)
Colonic Neoplasms (Phase 3)
Colorectal Neoplasms (Phase 4)
Common Cold (Phase 4)
Communicable Diseases (Phase 4)
Congenital Abnormalities (Phase 3)
Constipation (Phase 4)
Constriction, Pathologic (Phase 3)
Coronary Artery Disease (Phase 4)
Coronary Disease (Phase 4)
Coronary Stenosis (Phase 4)
Cough (Phase 2)
Cystic Fibrosis (Phase 2)
Depression (Phase 3)
Depressive Disorder (Phase 3)
Depressive Disorder, Major (Phase 3)
Dermatitis (Phase 4)
Dermatitis, Atopic (Phase 4)
Dermatitis, Contact (Phase 1)
Dermatitis, Perioral (Phase 2)
Dermatitis, Photoallergic (Phase 3)
Dermatitis, Phototoxic (Phase 3)
Dermatitis, Seborrheic (Phase 2)
Diabetes Mellitus (Phase 4)
Diabetes Mellitus, Type 1 (Phase 3)
Diabetes Mellitus, Type 2 (Phase 4)
Diabetic Foot (Phase 3)
Diabetic Nephropathies (Phase 4)
Diabetic Retinopathy (Phase 4)
Diarrhea (Phase 4)
Digestive System Diseases (Phase 2)
Digestive System Neoplasms (Phase 2)
Disease (Phase 3)
Disease Progression (Phase 2)
Down Syndrome (Phase 2)
Dysmenorrhea (Phase 4)
Eczema (Phase 4)
Edema (Phase 4)
Embolism (Phase 4)
Embolism and Thrombosis (Phase 4)
Emergencies (Phase 4)
Endometriosis (Phase 3)
Epilepsy (Phase 4)
Erectile Dysfunction (Phase 4)
Erysipelas (Phase 2)
Erythema (Phase 4)
Esophageal Neoplasms (Phase 3)
Essential Hypertension (Phase 4)
Eunuchism (Phase 4)
Eye Diseases (Phase 3)
Fallopian Tube Neoplasms (Phase 2)
Familial Primary Pulmonary Hypertension (Phase 4)
Fatigue (Phase 4)
Fatty Liver (Phase 4)
Febrile Neutropenia (Phase 3)
Fever (Phase 3)
Fibrosis (Phase 4)
Filariasis (Phase 1)
Frailty (Phase 4)
Gallbladder Neoplasms (Phase 2)
Gastrointestinal Diseases (Phase 2)
Gastrointestinal Neoplasms (Phase 2)
Gastrointestinal Stromal Tumors (Phase 3)
Glaucoma (Phase 3)
Glaucoma, Neovascular (Phase 3)
Glioblastoma (Phase 2)
Glioma (Phase 2)
Gliosarcoma (Phase 2)
Glucose Intolerance (Phase 4)
Graft vs Host Disease (Phase 2)
Headache (Phase 4)
Head and Neck Neoplasms (Phase 1)
Healthcare-Associated Pneumonia (Phase 2)
Heartburn (Phase 4)
Heart Diseases (Phase 4)
Heart Failure (Phase 3)
Heart Valve Diseases (Phase 3)
Hemangiosarcoma (Phase 2)
Hematologic Diseases (Phase 4)
Hematologic Neoplasms (Phase 1)
Hematoma (Phase 3)
Hemophilia A (Phase 4)
Hemophilia B (Phase 3)
Hemorrhage (Phase 4)
Hemostatic Disorders (Phase 3)
Hepatic Insufficiency (Phase 1)
Hidradenitis (Phase 2)
Hidradenitis Suppurativa (Phase 2)
HIV Infections (Phase 3)
Hodgkin Disease (Phase 2)
Hot Flashes (Phase 4)
Hyperandrogenism (Phase 4)
Hyperlipidemias (Phase 4)
Hyperlipoproteinemias (Phase 3)
Hyperphosphatemia (Phase 4)
Hyperpigmentation (Phase 4)
Hyperplasia (Phase 2)
Hypersensitivity (Phase 3)
Hypertension (Phase 4)
Hypertension, Pulmonary (Phase 4)
Hypertriglyceridemia (Phase 3)
Hypertrophy (Phase 2)
Hypogonadism (Phase 4)
Hypophosphatemia (Phase 1)
Hypothyroidism (Phase 4)
Idiopathic Interstitial Pneumonias (Phase 2)
Infarction (Phase 4)
Infections (Phase 4)
Infertility (Phase 4)
Infertility, Female (Phase 4)
Inflammation (Phase 1)
Insulin Resistance (Phase 4)
Intraabdominal Infections (Phase 3)
Irritable Bowel Syndrome (Phase 3)
Ischemia (Phase 3)
Ischemic Attack, Transient (Phase 2)
Kidney Diseases (Phase 4)
Kidney Failure, Chronic (Phase 3)
Kidney Neoplasms (Phase 2)
Leiomyoma (Phase 3)
Leiomyosarcoma (Phase 2)
Leukemia (Phase 3)
Leukemia, B-Cell (Phase 2)
