Organization Overview
Historical Acquisition Tree
Alternative names
acetaminophen (tylenol) (1997)
acetylsalicylic acid (aspirin) (1976)
alcaftadine (Lastacaft) (2010)
asenapine (saphris) (2009)
avibactam (Avycaz) (2015)
bimatoprost (lumigan) (2001 NDA)
Bismuth Subcitrate Potassium (Pylera) (2006)
brimonidine (alphagan) (1997 NDA)
butalbital (fiornal) (1976)
caffeine (1976)
cariprazine (vraylar) (2015)
ceftaroline fosamil (teflaro) (2010)
ceftazidime (fortaz) (2015)
chloramphenicol (chloromycetin) (1968)
citalopram (celexa) (1998 NDA)
codeine (Phenergan) (1990)
cromoglicic acid (Intal) (1984)
cyclosporine (sandimmune) (2002)
dalbavancin (dalvance) (2014)
dapsone (aczone) (2005)
darifenacin (enablex) (2004)
dexamethasone (2009)
diltiazem (cardizem) (1992)
dipivefrin (propine) (1980 NDA)
donepezil (aricept) (2014)
eluxadoline (viberzi) (2015)
epinastine (elestat) (2003 NDA)
escitalopram (lexapro) (2002)
estradiol (progynon depot) (1984)
ethinyl estradiol (Estinyl) (1973)
ethoxzolamide (ethamide) (1966 NDA)
etidronic acid (1977)
ferrous fumarate (2010)
fluorometholone (fml) (1972 NDA)
fluoxetine (prozac) (2006)
flurbiprofen (ansaid) (1986)
gatifloxacin (Zymar) (2003 NDA)
gentamicin (garamycin) (1984)
hydrochlorothiazide (esidrix) (1996)
hydrocodone (hycodan) (1997)
hydroxyprogesterone (Delalutin) (1974)
idoxuridine (herplex) (1963 NDA)
iron dextran (Imferon) (1974)
ketorolac (acuvail) (1992)
levobunolol (betagan) (1985 NDA)
levomilnacipran (fetzima) (2013)
levothyroxine (Synthroid) (1969)
linaclotide (linzess) (2012)
liothyronine (cytomel) (1969)
medrysone (hms) (1969)
memantine (namenda) (2003)
mesalamine (rowasa) (2001)
metronidazole (flagyl) (2006)
milnacipran (savella) (2009)
morphine (1996)
naphazoline (visine) (1972)
nebivolol (bystolic) (2007)
nedocromil (tilade) (1999)
neomycin (1963)
nitroglycerin (transderm-nitro) (2011)
norethindrone (1973)
ofloxacin (floxin) (1993)
onabotulinumtoxinA (Botox) (1991)
oxybutynin (ditropan) (2003)
podofilox (condylox) (1990 NDA)
polymyxin b sulfate (poly-rx) (1963)
prednisone (meticorten) (1961)
progesterone (progestasert) (1997)
proparacaine (ophthaine) (1961)
risedronate (actonel) (1998)
selenium (1974)
silodosin (rapaflo) (2008)
sucralfate (carafate) (1981)
sulfacetamide (sultrin) (1961)
tazarotene (tazorac) (1997 NDA)
testosterone (delatestryl) (1995)
tetracycline (tetrex) (2006)
timolol (blocadren) (2007)
tretinoin (Retin-A) (2010)
triamcinolone (kenalog) (2008)
trimethoprim (1988)
triptorelin (Trelstar) (2000)
trospium (sanctura) (2004)
ubrogepant (Ubrelvy) (2019 NDA)
urea (2009)
ursodeoxycholic acid (1987)
valsartan (diovan) (2016)
vilazodone (viibryd) (2011)
Key: Allergan (63) Acquired (1)
adapalene (differin) (4 trials)
aflibercept (zaltrap) (3 trials)
alcaftadine (Lastacaft) (6 trials)
benzoyl peroxide (clearasil) (2 trials)
bevacizumab (avastin) (8 trials)
bimatoprost (lumigan) (71 trials)
brimonidine (alphagan) (35 trials)
brinzolamide (azopt) (2 trials)
carboxymethyl cellulose (3 trials)
ceftaroline fosamil (teflaro) (1 trial)
cyclosporine (sandimmune) (17 trials)
dalbavancin (dalvance) (14 trials)
deoxycholic acid (kybella) (5 trials)
dorzolamide (trusopt) (4 trials)
duloxetine (Cymbalta) (1 trial)
eluxadoline (viberzi) (5 trials)
gatifloxacin (Zymar) (7 trials)
ketorolac (acuvail) (9 trials)
levomilnacipran (fetzima) (4 trials)
linaclotide (linzess) (10 trials)
metronidazole (flagyl) (2 trials)
minocycline (minocin) (1 trial)
moxifloxacin (avelox) (4 trials)
naphazoline (visine) (1 trial)
nepafenac (nevanac) (4 trials)
olopatadine (patanol) (4 trials)
omega-3 fatty acids (Omacor) (1 trial)
onabotulinumtoxinA (Botox) (34 trials)
oxybutynin (ditropan) (2 trials)
oxymetazoline (ocuclear) (4 trials)
pheniramine (Tripoton) (1 trial)
ranibizumab (lucentis) (18 trials)
rimabotulinumtoxinB (Myobloc) (129 trials)
tafluprost (zioptan) (1 trial)
tazarotene (tazorac) (5 trials)
testosterone (delatestryl) (2 trials)
timolol (blocadren) (35 trials)
tizanidine (zanaflex) (1 trial)
topiramate (topamax) (2 trials)
travoprost (travatan) (6 trials)
triamcinolone (kenalog) (7 trials)
Key: Allergan (33) Acquired (1)
budesonide (rhinocort) (6 trials)
cariprazine (vraylar) (12 trials)
dihydroergotamine (D.H.E. 45) (5 trials)
escitalopram (lexapro) (1 trial)
Abdominal Pain (Phase 2)
Acne Vulgaris (Phase 4)
Adenocarcinoma (Phase 2)
Alopecia (Phase 4)
Alopecia Areata (Phase 4)
Alzheimer Disease (Phase 1)
Amyotrophic Lateral Sclerosis (Phase 2)
Anxiety Disorders (Phase 3)
Arthritis (Phase 3)
Asthma (Phase 3)
Atrial Fibrillation (Phase 2)
Atrophy (Phase 2)
Autism Spectrum Disorder (Phase 1)
Autistic Disorder (Phase 1)
Bacteremia (Phase 2)
Bacterial Infections (Phase 4)
Bipolar Disorder (Phase 3)
Blepharospasm (Phase 4)
Blindness (Phase 2)
Brachial Plexus Neuritis (Phase 4)
Brain Injuries (Phase 4)
Brain Neoplasms (Phase 3)
Bruxism (Phase 4)
Capsule Opacification (Phase 2)
Carcinoma, Non-Small-Cell Lung (Phase 2)
Cardiovascular Diseases (Phase 4)
Carpal Tunnel Syndrome (Phase 2)
Cataract (Phase 4)
Cellulitis (Phase 4)
Cerebral Palsy (Phase 3)
Choroidal Neovascularization (Phase 2)
Chronic Disease (Phase 3)
Chronic Pain (Phase 2)
Cicatrix (Phase 2)
Cicatrix, Hypertrophic (Phase 2)
Colitis (Phase 2)
Colitis, Ulcerative (Phase 2)
Communicable Diseases (Phase 4)
Complex Regional Pain Syndromes (Phase 1)
Conjunctivitis (Phase 4)
Conjunctivitis, Allergic (Phase 4)
Conjunctivitis, Bacterial (Phase 4)
Constipation (Phase 4)
Corneal Ulcer (Phase 2)
Crohn Disease (Phase 3)
Cutis Laxa (Phase 1)
Cystitis (Phase 4)
Cystitis, Interstitial (Phase 4)
Depression (Phase 4)
Depressive Disorder (Phase 4)
Depressive Disorder, Major (Phase 4)
Diabetes Mellitus (Phase 4)
Diabetic Neuropathies (Phase 2)
Diabetic Retinopathy (Phase 4)
Diarrhea (Phase 4)
Disease (Phase 3)
Dry Eye Syndromes (Phase 4)
Dyskinesias (Phase 4)
Dyspareunia (Phase 2)
Dystonia (Phase 4)
Dystonic Disorders (Phase 4)
Edema (Phase 4)
Endocarditis (Phase 2)
Endocarditis, Bacterial (Phase 2)
Enuresis (Phase 4)
Epiretinal Membrane (Phase 4)
Erythema (Phase 3)
Essential Tremor (Phase 3)
Eye Abnormalities (Phase 2)
Eye Diseases (Phase 4)
Eye Diseases, Hereditary (Phase 2)
Eye Infections (Phase 4)
Facies (Phase 4)
Fatty Liver (Phase 3)
Febrile Neutropenia (Phase 2)
Fecal Incontinence (Phase 2)
Fever (Phase 2)
Fibromyalgia (Phase 4)
Gastroparesis (Phase 3)
Genetic Diseases, Inborn (Phase 2)
Geographic Atrophy (Phase 2)
Glaucoma (Phase 4)
Glaucoma, Angle-Closure (Phase 4)
Glaucoma, Open-Angle (Phase 4)
Gram-Negative Bacterial Infections (Phase 2)
Graves Ophthalmopathy (Phase 4)
Headache (Phase 3)
Healthcare-Associated Pneumonia (Phase 1)
Hemorrhage (Phase 3)
Hyperalgesia (Phase 2)
Hyperhidrosis (Phase 4)
Hyperopia (Phase 4)
Hyperplasia (Phase 2)
Hypertension (Phase 4)
Hypertrophy (Phase 4)
Hypertrophy, Left Ventricular (Phase 4)
Hypogonadism (Phase 4)
Hypothyroidism (Phase 2)
Hypotrichosis (Phase 4)
Infections (Phase 4)
Inflammation (Phase 4)
Iridocyclitis (Phase 3)
Irritable Bowel Syndrome (Phase 4)
Ischemia (Phase 4)
Joint Diseases (Phase 2)
Keratitis (Phase 2)
Keratoconjunctivitis (Phase 4)
Keratoconjunctivitis Sicca (Phase 4)
Lacrimal Apparatus Diseases (Phase 2)
Leber Congenital Amaurosis (Phase 2)
Leiomyoma (Phase 3)
Liver Cirrhosis (Phase 3)
Liver Diseases (Phase 1)
Low Tension Glaucoma (Phase 4)
Lung Neoplasms (Phase 2)
Macular Degeneration (Phase 3)
Macular Edema (Phase 4)
Melanoma (Phase 2)
Migraine Disorders (Phase 4)
Motor Neuron Disease (Phase 2)
Multiple Sclerosis (Phase 3)
Muscle Spasticity (Phase 4)
Myofascial Pain Syndromes (Phase 4)
Myofibroma (Phase 3)
Nausea (Phase 4)
Neoplasm Metastasis (Phase 3)
Neovascularization, Pathologic (Phase 2)
Neuralgia (Phase 4)
Neuralgia, Postherpetic (Phase 2)
Neutropenia (Phase 2)
Non-alcoholic Fatty Liver Disease (Phase 3)
Obesity (Phase 4)
Ocular Hypertension (Phase 4)
Osteoarthritis (Phase 2)
Osteoarthritis, Knee (Phase 2)
Osteomyelitis (Phase 3)
Pain (Phase 2)
Pancreatic Neoplasms (Phase 2)
Papilledema (Phase 3)
Paralysis (Phase 3)
Paresis (Phase 3)
Parkinson Disease (Phase 4)
Pars Planitis (Phase 4)
Patellofemoral Pain Syndrome (Phase 3)
Pelvic Pain (Phase 3)
Penile Induration (Phase 2)
Peptic Ulcer (Phase 1)
Pneumonia (Phase 4)
Pneumonia, Bacterial (Phase 4)
Postoperative Nausea and Vomiting (Phase 4)
Premature Birth (Phase 2)
Premature Ejaculation (Phase 2)
Presbyopia (Phase 3)
Prostatic Hyperplasia (Phase 2)
Prostatitis (Phase 3)
Pruritus (Phase 2)
Psoriasis (Phase 2)
Pterygium (Phase 2)
Raynaud Disease (Phase 3)
Rectal Neoplasms (Phase 2)
Recurrence (Phase 4)
Reflex Sympathetic Dystrophy (Phase 1)
Renal Insufficiency (Phase 1)
Retinal Degeneration (Phase 2)
Retinal Detachment (Phase 2)
Retinal Diseases (Phase 4)
Retinal Vein Occlusion (Phase 4)
Retinitis (Phase 2)
Retinitis Pigmentosa (Phase 2)
Rhinitis (Phase 3)
Rhinitis, Allergic (Phase 3)
Rhinitis, Allergic, Seasonal (Phase 3)
Rosacea (Phase 4)
Schizophrenia (Phase 3)
Scleroderma, Diffuse (Phase 3)
Scleroderma, Localized (Phase 3)
Scleroderma, Systemic (Phase 3)
Sclerosis (Phase 3)
Shoulder Pain (Phase 4)
Sialorrhea (Phase 3)
Sjogren's Syndrome (Phase 4)
Skin Diseases, Bacterial (Phase 4)
Skin Diseases, Infectious (Phase 4)
Somatoform Disorders (Phase 3)
Spinal Cord Injuries (Phase 4)
Staphylococcal Skin Infections (Phase 3)
Stroke (Phase 3)
Surgical Wound (Phase 2)
Surgical Wound Infection (Phase 3)
Syndrome (Phase 4)
Temporomandibular Joint Disorders (Phase 3)
Thoracic Outlet Syndrome (Phase 2)
Thyroid Diseases (Phase 2)
Torticollis (Phase 4)
Tremor (Phase 3)
Ulcer (Phase 2)
Urinary Bladder Neoplasms (Phase 3)
Urinary Bladder, Neurogenic (Phase 4)
Urinary Bladder, Overactive (Phase 4)
Urinary Incontinence (Phase 4)
Urinary Incontinence, Urge (Phase 2)
Uterine Hemorrhage (Phase 3)
Uveal Neoplasms (Phase 2)
Uveitis (Phase 4)
Uveitis, Anterior (Phase 3)
Uveitis, Intermediate (Phase 4)
Uveitis, Posterior (Phase 4)
Vaginal Diseases (Phase 4)
Vaginismus (Phase 1)
Vaginosis, Bacterial (Phase 4)
Vision Disorders (Phase 2)
Vomiting (Phase 4)
Wound Infection (Phase 3)
Wounds and Injuries (Phase 4)
