Organization Overview
Historical Acquisition Tree
Alternative names
amiodarone (cordarone) (1985 NDA)
bazedoxifene (Duavee) (2013)
bosutinib (bosulif) (2012 NDA)
brompheniramine maleate (dimetane) (1957 NDA)
carphenazine (proketazine) (1963 NDA)
ceftolozane (Zerbaxa) (NDA)
clofibrate (atromid-s) (1967 NDA)
conjugated equine estrogens (1994)
cyclacillin (cyclapen-w) (1979 NDA)
daunorubicin (cerubidine) (1979 NDA)
desvenlafaxine (pristiq) (2008 NDA)
dicloxacillin (pathocil) (1968 NDA)
echothiophate (phospholine iodide) (1960 NDA)
epinephrine (levophed) (1967)
ethinyl estradiol (Estinyl) (1968)
ethionamide (trecator) (1965)
etodolac (lodine) (1991 NDA)
folic acid (1947)
gemtuzumab ozogamicin (mylotarg) (2000)
gonadorelin (factrel) (1982 NDA)
griseofulvin (grisactin) (1962 NDA)
halothane (fluothane) (1958 NDA)
hydrochlorothiazide (esidrix) (1979)
ibuprofen (motrin) (1989)
inotuzumab ozogamicin (besponsa) (2017)
ketoprofen (orudis) (1995)
medroxyprogesterone (provera) (1994)
meprobamate (equanil) (1955 NDA)
nafcillin (unipen) (1965 NDA)
norgestrel (Ovral) (1984)
pantoprazole (protonix) (2000)
pentagastrin (peptavlon) (1974 NDA)
pentolinium (ansolysen) (1954 NDA)
piperacillin (pipracil) (1981)
pralidoxime (protopam chloride) (1964 NDA)
promazine hydrochloride (sparine) (1957 NDA)
propranolol (inderal) (1967)
quinidine (1962)
sulfamethizole (thiosulfil) (1953 NDA)
tazobactam (Zosyn) (NDA)
tigecycline (tygacil) (2005 NDA)
venlafaxine (effexor) (1997)
23-valent pneumococcal polysaccharide vaccine (pneumovax-23) (2 trials)
allogeneic blood cells (1 trial)
antihemophilic factor viii human (Hemofil M) (5 trials)
antihemophilic factor viii (Recombinant) (Adynovate) (1 trial)
Anti-thymocyte Globulin (Rabbit) (Thymoglobulin) (1 trial)
azacitidine (vidaza) (1 trial)
ceftriaxone (rocephin) (2 trials)
citalopram (celexa) (2 trials)
coagulation factor ix (Recombinant) (Rixubis) (5 trials)
codeine (Phenergan) (2 trials)
conjugated equine estrogens (21 trials)
diphtheria-tetanus-acellular pertussis-inactivated poliovirus-haemophilus influenzae b conjugate-hepatitis b vaccine (2 trials)
duloxetine (Cymbalta) (2 trials)
ergocalciferol (drisdol) (1 trial)
escitalopram (lexapro) (3 trials)
estradiol (progynon depot) (2 trials)
etanercept (enbrel) (56 trials)
ethinyl estradiol (Estinyl) (9 trials)
gemtuzumab ozogamicin (mylotarg) (8 trials)
methylnaltrexone (relistor) (8 trials)
methylprednisolone (medrol) (4 trials)
metronidazole (flagyl) (2 trials)
mycophenolate (myfortic) (11 trials)
naltrexone (revia) (11 trials)
pantoprazole (protonix) (14 trials)
piperacillin (pipracil) (10 trials)
pneumococcal 13-valent conjugate vaccine (prevnar 13) (11 trials)
pneumococcal 7-valent conjugate vaccine (prevnar) (17 trials)
acetylsalicylic acid (aspirin) (1 trial)
amiodarone (cordarone) (1 trial)
aripiprazole (abilify) (1 trial)
bazedoxifene (Duavee) (12 trials)
bosutinib (bosulif) (12 trials)
cilastatin (primaxin) (1 trial)
cisplatin (platinol) (2 trials)
clobetasol (dermovate) (1 trial)
inactivated influenza vaccine (1 trial)
levofloxacin (levaquin) (1 trial)
live attenuated influenza virus vaccine (flumist) (20 trials)
medroxyprogesterone (provera) (4 trials)
atorvastatin (lipitor) (1 trial)
bendamustine (treanda) (2 trials)
bevacizumab (avastin) (1 trial)
bicalutamide (casodex) (1 trial)
bone morphogenetic protein-2 (3 trials)
cytarabine (cytosar-u) (1 trial)
dexchlorpheniramine maleate (polaramine) (1 trial)
donepezil (aricept) (2 trials)
Abdominal Abscess (Phase 4)
Abscess (Phase 4)
Acalculous Cholecystitis (Phase 4)
Adenocarcinoma (Phase 1)
Alzheimer Disease (Phase 3)
Anemia, Sickle Cell (Phase 4)
Anxiety Disorders (Phase 4)
Apnea (Phase 4)
Appendicitis (Phase 4)
Arrhythmias, Cardiac (Phase 2)
Arthritis (Phase 4)
Arthritis, Psoriatic (Phase 4)
Arthritis, Rheumatoid (Phase 4)
Asthma (Phase 3)
Atrial Fibrillation (Phase 3)
Atrophic Vaginitis (Phase 3)
Atrophy (Phase 3)
Bacterial Infections (Phase 4)
Bipolar Disorder (Phase 3)
Body Weight (Phase 4)
Body Weight Changes (Phase 3)
Brain Neoplasms (Phase 1)
Breast Neoplasms (Phase 3)
Breast Neoplasms, Male (Phase 1)
Carcinoid Tumor (Phase 1)
Carcinoma (Phase 2)
Carcinoma, Hepatocellular (Phase 2)
Carcinoma, Islet Cell (Phase 1)
Carcinoma, Medullary (Phase 1)
Carcinoma, Merkel Cell (Phase 1)
Carcinoma, Neuroendocrine (Phase 1)
Carcinoma, Non-Small-Cell Lung (Phase 2)
Carcinoma, Ovarian Epithelial (Phase 1)
Carcinoma, Renal Cell (Phase 2)
Cardiovascular Diseases (Phase 3)
Carotid Body Tumor (Phase 1)
Central Nervous System Neoplasms (Phase 1)
Cholecystitis (Phase 4)
Colitis (Phase 1)
Colitis, Ulcerative (Phase 1)
Colonic Neoplasms (Phase 3)
Colorectal Neoplasms (Phase 2)
Communicable Diseases (Phase 4)
Community-Acquired Infections (Phase 3)
Constipation (Phase 4)
Coronary Artery Disease (Phase 3)
Coronary Disease (Phase 3)
Crohn Disease (Phase 2)
Cross Infection (Phase 4)
Delayed Graft Function (Phase 4)
Depression (Phase 4)
Depressive Disorder (Phase 4)
Depressive Disorder, Major (Phase 4)
Diabetes Mellitus (Phase 2)
Diabetes Mellitus, Type 1 (Phase 3)
Diabetes Mellitus, Type 2 (Phase 2)
Diabetic Foot (Phase 4)
Diabetic Nephropathies (Phase 3)
Diabetic Neuropathies (Phase 3)
Disease (Phase 3)
Diverticulitis (Phase 4)
Dysmenorrhea (Phase 2)
Dyspareunia (Phase 2)
Emergencies (Phase 4)
Endometrial Hyperplasia (Phase 3)
Endometrial Neoplasms (Phase 1)
Endometriosis (Phase 2)
Enthesopathy (Phase 4)
Esophageal Diseases (Phase 4)
Esophagitis (Phase 4)
Esophagitis, Peptic (Phase 4)
Fallopian Tube Neoplasms (Phase 1)
Fever (Phase 4)
Fibromyalgia (Phase 3)
Fibrosis (Phase 4)
Fractures, Bone (Phase 4)
Fractures, Closed (Phase 2)
Gastroesophageal Reflux (Phase 4)
Gastrointestinal Neoplasms (Phase 1)
Genital Neoplasms, Female (Phase 1)
Germinoma (Phase 1)
Glioblastoma (Phase 2)
Glomerulonephritis (Phase 2)
Glomerulonephritis, IGA (Phase 2)
Glomerulonephritis, Membranous (Phase 1)
Glucose Intolerance (Phase 3)
Glucose Metabolism Disorders (Phase 3)
Graft vs Host Disease (Phase 4)
Gram-Negative Bacterial Infections (Phase 3)
Gram-Positive Bacterial Infections (Phase 3)
Heartburn (Phase 4)
Heart Diseases (Phase 3)
Hematologic Neoplasms (Phase 3)
Hemophilia A (Phase 4)
Hemophilia B (Phase 4)
Hemorrhage (Phase 3)
Hepatic Insufficiency (Phase 1)
Hepatitis (Phase 1)
Hepatitis C (Phase 1)
HIV Infections (Phase 2)
Hodgkin Disease (Phase 2)
Hot Flashes (Phase 4)
Hyperplasia (Phase 3)
Hypersensitivity (Phase 2)
Hypertension (Phase 4)
Idiopathic Pulmonary Fibrosis (Phase 2)
Ileus (Phase 3)
Infections (Phase 4)
Inflammation (Phase 3)
Inflammatory Bowel Diseases (Phase 2)
Influenza, Human (Phase 3)
Intraabdominal Infections (Phase 4)
Ischemia (Phase 1)
Joint Diseases (Phase 4)
Kidney Diseases (Phase 4)
Kidney Failure, Chronic (Phase 4)
Leiomyoma (Phase 1)
Leukemia (Phase 4)
Leukemia, Lymphoid (Phase 1)
Leukemia, Myeloid (Phase 4)
Leukemia, Myeloid, Acute (Phase 4)
Leukemia, Promyelocytic, Acute (Phase 3)
Liver Failure (Phase 1)
Long QT Syndrome (Phase 1)
Lung Diseases (Phase 2)
Lung Diseases, Interstitial (Phase 4)
Lung Neoplasms (Phase 2)
Lupus Erythematosus, Systemic (Phase 1)
Lymphangioleiomyomatosis (Phase 2)
Lymphoma (Phase 2)
Lymphoma, B-Cell (Phase 2)
Lymphoma, Follicular (Phase 2)
Lymphoma, Mantle-Cell (Phase 2)
Lymphoma, Non-Hodgkin (Phase 2)
Malignant Carcinoid Syndrome (Phase 1)
Meningitis (Phase 2)
Meningitis, Meningococcal (Phase 2)
Menorrhagia (Phase 2)
Menstruation Disturbances (Phase 3)
Metabolic Diseases (Phase 3)
Multiple Myeloma (Phase 2)
Multiple Sclerosis (Phase 3)
Multiple Sclerosis, Chronic Progressive (Phase 3)
Multiple Sclerosis, Relapsing-Remitting (Phase 2)
Muscular Dystrophies (Phase 2)
Muscular Dystrophies, Limb-Girdle (Phase 2)
Muscular Dystrophy, Duchenne (Phase 2)
Muscular Dystrophy, Facioscapulohumeral (Phase 2)
Mycobacterium Infections (Phase 2)
Myelodysplastic Syndromes (Phase 3)
Myocardial Ischemia (Phase 3)
Myofascial Pain Syndromes (Phase 3)
Myofibroma (Phase 1)
Neoplasm Metastasis (Phase 3)
Neoplasms (Phase 3)
Neoplasms, Germ Cell and Embryonal (Phase 1)
Neoplasms, Plasma Cell (Phase 2)
Nervous System Neoplasms (Phase 1)
Neuralgia (Phase 2)
Osteoarthritis (Phase 4)
Osteoarthritis, Knee (Phase 2)
Osteomyelitis (Phase 3)
Osteoporosis (Phase 3)
Osteoporosis, Postmenopausal (Phase 2)
Otitis (Phase 3)
Otitis Media (Phase 3)
Ovarian Neoplasms (Phase 1)
Overweight (Phase 4)
Pancreatic Neoplasms (Phase 1)
Panic Disorder (Phase 3)
Paraganglioma (Phase 1)
Parasomnias (Phase 4)
Parkinson Disease (Phase 2)
Pelvic Pain (Phase 2)
Peptic Ulcer (Phase 3)
Peptic Ulcer Hemorrhage (Phase 3)
Peripheral Nervous System Diseases (Phase 3)
Peritonitis (Phase 4)
Pheochromocytoma (Phase 1)
Philadelphia Chromosome (Phase 3)
Phobia, Social (Phase 3)
Pneumococcal Infections (Phase 4)
Pneumonia (Phase 3)
Pneumonia, Bacterial (Phase 3)
Polycystic Kidney, Autosomal Dominant (Phase 2)
Polycystic Kidney Diseases (Phase 3)
Preleukemia (Phase 3)
Premenstrual Dysphoric Disorder (Phase 3)
Premenstrual Syndrome (Phase 3)
Prostatic Neoplasms (Phase 2)
Psoriasis (Phase 4)
Psychotic Disorders (Phase 3)
Pulmonary Fibrosis (Phase 2)
Radius Fractures (Phase 1)
Rectal Neoplasms (Phase 2)
Recurrence (Phase 4)
Renal Insufficiency (Phase 4)
Renal Insufficiency, Chronic (Phase 4)
Respiratory Tract Infections (Phase 3)
Retinal Vein Occlusion (Phase 2)
Rubella (Phase 2)
Sarcoma (Phase 2)
Schizophrenia (Phase 3)
Scleritis (Phase 1)
Sclerosis (Phase 3)
Skin Diseases (Phase 4)
Skin Diseases, Bacterial (Phase 4)
Skin Diseases, Infectious (Phase 4)
Skin Neoplasms (Phase 4)
Sleep Apnea, Obstructive (Phase 4)
Sleep Apnea Syndromes (Phase 4)
Sleepiness (Phase 4)
Sleep Wake Disorders (Phase 4)
Small Cell Lung Carcinoma (Phase 1)
Spondylarthritis (Phase 2)
Spondylarthropathies (Phase 4)
Spondylitis (Phase 4)
Spondylitis, Ankylosing (Phase 4)
Staphylococcal Infections (Phase 4)
Stomach Neoplasms (Phase 3)
Stroke (Phase 1)
Syndrome (Phase 2)
Synovitis (Phase 2)
Tachycardia (Phase 2)
Tachycardia, Ventricular (Phase 2)
Thrombocytopenia (Phase 2)
Tibial Fractures (Phase 4)
Toothache (Phase 3)
Triple Negative Breast Neoplasms (Phase 1)
Tuberous Sclerosis (Phase 2)
Ulcer (Phase 3)
Urinary Bladder Neoplasms (Phase 2)
Uterine Cervical Neoplasms (Phase 1)
Vaginitis (Phase 3)
von Willebrand Diseases (Phase 2)