Diseases [C] » Hemic and Lymphatic Diseases [C15] » Hematologic Diseases » Blood Platelet Disorders » Thrombocytopenia » Thrombotic Microangiopathies
Description
Diseases that result in THROMBOSIS in MICROVASCULATURE. The two most prominent diseases are PURPURA, THROMBOTIC THROMBOCYTOPENIC; and HEMOLYTIC-UREMIC SYNDROME. Multiple etiological factors include VASCULAR ENDOTHELIAL CELL damage due to SHIGA TOXIN; FACTOR H deficiency; and aberrant VON WILLEBRAND FACTOR formation. MeSH
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Subtype Terms (2)
Hemolytic-Uremic Syndrome
5 drugs (3 approved, 2 experimental)
Purpura, Thrombocytopenic
8 drugs (7 approved, 1 experimental)
Phase 3 Indicated Drugs (4)
Phase 2 Indicated Drugs (3)
Other Experimental Indicated Drugs (1)
Organization Involved with Phase 3 Indications (4)
Organization Involved with Phase 2 Indications (3)
Organization Involved with Other Experimental Indications (1)
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UMLS Data
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