Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Intracellular Signaling Peptides and Proteins » Protein Serine-Threonine Kinases » Proline-Directed Protein Kinases » Cyclin-Dependent Kinases » Cyclin-Dependent Kinase 4
Chemicals and Drugs [D] » Enzymes and Coenzymes [D08] » Enzymes » Transferases » Phosphotransferases » Phosphotransferases (Alcohol Group Acceptor) » Protein Kinases » Protein Serine-Threonine Kinases » Proline-Directed Protein Kinases » Cyclin-Dependent Kinases » Cyclin-Dependent Kinase 4
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Cell Cycle Proteins » Cyclin-Dependent Kinases » Cyclin-Dependent Kinase 4
Description
Cyclin-dependent kinase 4 is a key regulator of G1 PHASE of the CELL CYCLE. It partners with CYCLIN D to phosphorylate RETINOBLASTOMA PROTEIN. CDK4 activity is inhibited by CYCLIN-DEPENDENT KINASE INHIBITOR P16. MeSH
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