Diseases [C] » Nervous System Diseases [C10] » Neurodegenerative Diseases » Tauopathies
Description
Neurodegenerative disorders involving deposition of abnormal tau protein isoforms (TAU PROTEINS) in neurons and glial cells in the brain. Pathological aggregations of tau proteins are associated with mutation of the tau gene on chromosome 17 in patients with ALZHEIMER DISEASE; DEMENTIA; PARKINSONIAN DISORDERS; progressive supranuclear palsy (SUPRANUCLEAR PALSY, PROGRESSIVE); and corticobasal degeneration. MeSH
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Subtype Terms (4)
Alzheimer Disease
600 drugs (189 approved, 411 experimental)
Corticobasal Degeneration
15 drugs (10 approved, 5 experimental)
Diffuse Neurofibrillary Tangles with Calcification
Supranuclear Palsy, Progressive
47 drugs (20 approved, 27 experimental)
Phase 2 Indicated Drugs (3)
Phase 1 Indicated Drugs (2)
Other Experimental Indicated Drugs (1)
Organization Involved with Phase 2 Indications (10)
Organization Involved with Phase 1 Indications (8)
Organization Involved with Other Experimental Indications (1)
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UMLS Data
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