Related MeSH Hierarchy (6)
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Intracellular Signaling Peptides and Proteins » Protein-Tyrosine Kinases » Receptor Protein-Tyrosine Kinases » ErbB Receptors » Receptor, ErbB-3
Chemicals and Drugs [D] » Enzymes and Coenzymes [D08] » Enzymes » Transferases » Phosphotransferases » Phosphotransferases (Alcohol Group Acceptor) » Protein Kinases » Protein-Tyrosine Kinases » Receptor Protein-Tyrosine Kinases » ErbB Receptors » Receptor, ErbB-3
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Membrane Proteins » Receptors, Cell Surface » Receptor Protein-Tyrosine Kinases » ErbB Receptors » Receptor, ErbB-3
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Membrane Proteins » Receptors, Cell Surface » Receptors, Peptide » Receptors, Growth Factor » ErbB Receptors » Receptor, ErbB-3
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Neoplasm Proteins » Oncogene Proteins » Proto-Oncogene Proteins » Receptor, ErbB-3
Chemicals and Drugs [D] » Biological Factors [D23] » Biomarkers » Biomarkers, Tumor » Receptor, ErbB-3
Description
A cell surface protein-tyrosine kinase receptor that is specific for NEUREGULINS. It has extensive homology to and can heterodimerize with the EGF RECEPTOR and the ERBB-2 RECEPTOR. Overexpression of the erbB-3 receptor is associated with TUMORIGENESIS. MeSH
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