Related MeSH Hierarchy (8)
Phenomena and Processes [G] » Chemical Phenomena [G02] » Biochemical Phenomena » Molecular Structure » Base Sequence » Repetitive Sequences, Nucleic Acid » Tandem Repeat Sequences » DNA Repeat Expansion » Trinucleotide Repeat Expansion
Phenomena and Processes [G] » Genetic Phenomena [G05] » Mutagenesis » DNA Repeat Expansion » Trinucleotide Repeat Expansion
Phenomena and Processes [G] » Genetic Phenomena [G05] » Genetic Structures » Genome » Genome Components » Tandem Repeat Sequences » Microsatellite Repeats » Trinucleotide Repeats » Trinucleotide Repeat Expansion
Phenomena and Processes [G] » Chemical Phenomena [G02] » Biochemical Phenomena » Molecular Structure » Base Sequence » Repetitive Sequences, Nucleic Acid » Tandem Repeat Sequences » Microsatellite Repeats » Trinucleotide Repeats » Trinucleotide Repeat Expansion
Phenomena and Processes [G] » Genetic Phenomena [G05] » Genetic Structures » Base Sequence » Repetitive Sequences, Nucleic Acid » Tandem Repeat Sequences » DNA Repeat Expansion » Trinucleotide Repeat Expansion
Phenomena and Processes [G] » Genetic Phenomena [G05] » Genetic Structures » Base Sequence » Repetitive Sequences, Nucleic Acid » Tandem Repeat Sequences » Microsatellite Repeats » Trinucleotide Repeats » Trinucleotide Repeat Expansion
Phenomena and Processes [G] » Genetic Phenomena [G05] » Genetic Structures » Genome » Genome Components » DNA Sequence, Unstable » DNA Repeat Expansion » Trinucleotide Repeat Expansion
Phenomena and Processes [G] » Genetic Phenomena [G05] » Genetic Variation » Mutation » DNA Repeat Expansion » Trinucleotide Repeat Expansion
Description
An increased number of contiguous trinucleotide repeats in the DNA sequence from one generation to the next. The presence of these regions is associated with diseases such as FRAGILE X SYNDROME and MYOTONIC DYSTROPHY. Some CHROMOSOME FRAGILE SITES are composed of sequences where trinucleotide repeat expansion occurs. MeSH
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