Respiratory Burst D016897

Phenomena and Processes [G] » Metabolism [G03] » Cell Respiration » Respiratory Burst

Phenomena and Processes [G] » Cell Physiological Phenomena [G04] » Cell Respiration » Respiratory Burst

Description

A large increase in oxygen uptake by neutrophils and most types of tissue macrophages through activation of an NADPH-cytochrome b-dependent oxidase that reduces oxygen to a superoxide. Individuals with an inherited defect in which the oxidase that reduces oxygen to superoxide is decreased or absent (GRANULOMATOUS DISEASE, CHRONIC) often die as a result of recurrent bacterial infections.   MeSH

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