Ocular Motility Disorders D015835

Diseases [C] » Nervous System Diseases [C10] » Central Nervous System Diseases » Ocular Motility Disorders

Diseases [C] » Nervous System Diseases [C10] » Cranial Nerve Diseases » Ocular Motility Disorders

Diseases [C] » Eye Diseases [C11] » Ocular Motility Disorders

Description

Disorders that feature impairment of eye movements as a primary manifestation of disease. These conditions may be divided into infranuclear, nuclear, and supranuclear disorders. Diseases of the eye muscles or oculomotor cranial nerves (III, IV, and VI) are considered infranuclear. Nuclear disorders are caused by disease of the oculomotor, trochlear, or abducens nuclei in the BRAIN STEM. Supranuclear disorders are produced by dysfunction of higher order sensory and motor systems that control eye movements, including neural networks in the CEREBRAL CORTEX; BASAL GANGLIA; CEREBELLUM; and BRAIN STEM. Ocular torticollis refers to a head tilt that is caused by an ocular misalignment. Opsoclonus refers to rapid, conjugate oscillations of the eyes in multiple directions, which may occur as a parainfectious or paraneoplastic condition (e.g., OPSOCLONUS-MYOCLONUS SYNDROME). (Adams et al., Principles of Neurology, 6th ed, p240)   MeSH

Subtype Terms (8)

Duane Retraction Syndrome
 

Miller Fisher Syndrome
2 approved drugs

Nystagmus, Pathologic
4 drugs (3 approved, 1 experimental)

Oculomotor Nerve Diseases
 

Ophthalmoplegia
2 drugs (1 approved, 1 experimental)

Opsoclonus-Myoclonus Syndrome
12 drugs (9 approved, 3 experimental)

Strabismus
20 drugs (17 approved, 3 experimental)

Tolosa-Hunt Syndrome
 


Phase 2 Indicated Drugs (1)


Organization Involved with Phase 3 Indications (1)

Hierarchy Tree View

UMLS Data


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