Giant Cells, Langhans D015744

Related MeSH Hierarchy (6)

Anatomy [A] » Cells [A11] » Phagocytes » Macrophages » Giant Cells, Langhans

Anatomy [A] » Cells [A11] » Connective Tissue Cells » Macrophages » Giant Cells, Langhans

Anatomy [A] » Cells [A11] » Giant Cells » Giant Cells, Langhans

Anatomy [A] » Cells [A11] » Myeloid Cells » Macrophages » Giant Cells, Langhans

Anatomy [A] » Hemic and Immune Systems [A15] » Immune System » Mononuclear Phagocyte System » Macrophages » Giant Cells, Langhans

Anatomy [A] » Hemic and Immune Systems [A15] » Immune System » Phagocytes » Macrophages » Giant Cells, Langhans

Description

Multinucleated cells (fused macrophages) seen in granulomatous inflammations such as tuberculosis, syphilis, sarcoidosis, and deep fungal infections. They resemble foreign-body giant cells (GIANT CELLS, FOREIGN BODY) but Langhans giant cells contain less chromatin and their nuclei are arranged peripherally in a horseshoe-shaped pattern. Langhans giant cells occur frequently in delayed hypersensitivity.   MeSH

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