Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Neoplasm Proteins » Oncogene Proteins » Proto-Oncogene Proteins
Description
Products of proto-oncogenes. Normally they do not have oncogenic or transforming properties, but are involved in the regulation or differentiation of cell growth. They often have protein kinase activity. MeSH
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Subtype Terms (64)
Cyclin D1
9 approved drugs
Lymphocyte Specific Protein Tyrosine Kinase p56(lck)
MDS1 and EVI1 Complex Locus Protein
Myeloid-Lymphoid Leukemia Protein
N-Myc Proto-Oncogene Protein
10 drugs (8 approved, 2 experimental)
Pre-B-Cell Leukemia Transcription Factor 1
Proto-Oncogene Proteins c-akt
1 experimental drug
Proto-Oncogene Proteins c-bcl-6
Proto-Oncogene Proteins c-kit
3 approved drugs
Proto-Oncogene Proteins c-mdm2
Proto-Oncogene Proteins c-met
13 drugs (9 approved, 4 experimental)
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