Pharmacokinetics D010599

Phenomena and Processes [G] » Metabolism [G03] » Pharmacokinetics

Phenomena and Processes [G] » Physiological Phenomena [G07] » Pharmacological and Toxicological Phenomena » Pharmacokinetics

Description

Dynamic and kinetic mechanisms of exogenous chemical DRUG LIBERATION; ABSORPTION; BIOLOGICAL TRANSPORT; TISSUE DISTRIBUTION; BIOTRANSFORMATION; elimination; and DRUG TOXICITY as a function of dosage, and rate of METABOLISM. LADMER, ADME and ADMET are abbreviations for liberation, absorption, distribution, metabolism, elimination, and toxicology.   MeSH

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Subtype Terms (10)

Absorption
8 drugs (2 approved, 6 experimental)

Area Under Curve
3 approved drugs

Biological Availability
82 drugs (55 approved, 27 experimental)

Biotransformation
 

Therapeutic Equivalency
112 drugs (88 approved, 24 experimental)

Tissue Distribution
 


Phase 4 Indicated Drugs (71)

Phase 1 Indicated Drugs (336)

cefazolin (ancef)

cefepime (maxipeme)

ceftaroline fosamil (teflaro)

ceftazidime (fortaz)

cj-12420

clarithromycin (biaxin)

clonazepam (klonopin)

cobicistat (stribild)

cocaine (Erythroxyline)

curcumin

d961

dabigatran (pradaxa)

darexaban

darolutamide (Nubeqa)

darunavir (prezista)

dehydroepiandrosterone

denosumab (prolia)

desipramine (pertofrane)

dexmecamylamine

dextromethorphan (delsym)

diclofenac (voltaren)

dienogest (natazia)

digoxin (lanoxin)

dihydroqinghaosu

diltiazem (cardizem)

diphenylcyclopropenone

diractin

docetaxel (taxotere)

dofetilide (tikosyn)

ds-1971

ds-8500a

dtri-031

edaravone (radicava)

efavirenz (sustiva)

eflapegrastim

enalapril (vasotec)

enclomiphene citrate

endostatin (endostar)

entacapone (comtan)

entospletinib

enzalutamide (xtandi)

erythromycin (ilosone)

esomeprazole (nexium)

ethinyl estradiol (Estinyl)

etoricoxib (Gencox)

etravirine (intelence)

evolocumab (repatha)

ezetimibe (zetia)

f573

fasiglifam

faxeladol

fenofibrate (fenoglide)

fexofenadine (allegra)

fidaxomicin (dificid)

filgrastim (neupogen)

fimasartan (kanarb)

finafloxacin (xtoro)

finerenone

fludrocortisone (florinef)

fluvoxamine (luvox)

folic acid

follitropin alfa

fostamatinib

fremanezumab

funapide

furosemide (lasix)

gadopiclenol

galantamine (reminyl)

gemfibrozil (lopid)

gft505

gilteritinib

glimepiride (amaryl)

glycopyrrolate

grapefruit juice

gs-248

hexyl 5-aminolevulinate (Cysview)

hs-10296

htl0018318

hutrukin

hydrochlorothiazide (esidrix)

hydrocodone (hycodan)

hydronidone

icaritin

icosapent ethyl (vascepa)

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