Related MeSH Hierarchy (7)
Diseases [C] » Nervous System Diseases [C10] » Autonomic Nervous System Diseases » Primary Dysautonomias » Multiple System Atrophy » Olivopontocerebellar Atrophies
Diseases [C] » Nervous System Diseases [C10] » Central Nervous System Diseases » Brain Diseases » Basal Ganglia Diseases » Multiple System Atrophy » Olivopontocerebellar Atrophies
Diseases [C] » Nervous System Diseases [C10] » Central Nervous System Diseases » Brain Diseases » Cerebellar Diseases » Spinocerebellar Degenerations » Olivopontocerebellar Atrophies
Diseases [C] » Nervous System Diseases [C10] » Central Nervous System Diseases » Movement Disorders » Multiple System Atrophy » Olivopontocerebellar Atrophies
Diseases [C] » Nervous System Diseases [C10] » Central Nervous System Diseases » Spinal Cord Diseases » Spinocerebellar Degenerations » Olivopontocerebellar Atrophies
Diseases [C] » Nervous System Diseases [C10] » Neurodegenerative Diseases » Heredodegenerative Disorders, Nervous System » Spinocerebellar Degenerations » Olivopontocerebellar Atrophies
Diseases [C] » Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16] » Genetic Diseases, Inborn » Heredodegenerative Disorders, Nervous System » Spinocerebellar Degenerations » Olivopontocerebellar Atrophies
Description
A group of inherited and sporadic disorders which share progressive ataxia in combination with atrophy of the CEREBELLUM; PONS; and inferior olivary nuclei. Additional clinical features may include MUSCLE RIGIDITY; NYSTAGMUS, PATHOLOGIC; RETINAL DEGENERATION; MUSCLE SPASTICITY; DEMENTIA; URINARY INCONTINENCE; and OPHTHALMOPLEGIA. The familial form has an earlier onset (second decade) and may feature spinal cord atrophy. The sporadic form tends to present in the fifth or sixth decade, and is considered a clinical subtype of MULTIPLE SYSTEM ATROPHY. (From Adams et al., Principles of Neurology, 6th ed, p1085) MeSH
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