Diseases [C] » Nervous System Diseases [C10] » Nervous System Malformations » Neural Tube Defects
Diseases [C] » Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16] » Congenital Abnormalities » Nervous System Malformations » Neural Tube Defects
Description
Congenital malformations of the central nervous system and adjacent structures related to defective neural tube closure during the first trimester of pregnancy generally occurring between days 18-29 of gestation. Ectodermal and mesodermal malformations (mainly involving the skull and vertebrae) may occur as a result of defects of neural tube closure. (From Joynt, Clinical Neurology, 1992, Ch55, pp31-41) MeSH
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Subtype Terms (7)
Spinal Dysraphism
3 approved drugs
Phase 3 Indicated Drugs (5)
Phase 1 Indicated Drugs (1)
Other Experimental Indicated Drugs (1)
Organization Involved with Phase 3 Indications (2)
Organization Involved with Phase 2 Indications (2)
Organization Involved with Phase 1 Indications (2)
Organization Involved with Other Experimental Indications (5)
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UMLS Data
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