Multiple Endocrine Neoplasia D009377

Related MeSH Hierarchy (5)

Diseases [C] » Neoplasms [C04] » Neoplasms by Site » Endocrine Gland Neoplasms » Multiple Endocrine Neoplasia

Diseases [C] » Neoplasms [C04] » Neoplasms, Multiple Primary » Multiple Endocrine Neoplasia

Diseases [C] » Neoplasms [C04] » Neoplastic Syndromes, Hereditary » Multiple Endocrine Neoplasia

Diseases [C] » Endocrine System Diseases [C19] » Endocrine Gland Neoplasms » Multiple Endocrine Neoplasia

Description

A group of autosomal dominant diseases characterized by the combined occurrence of tumors involving two or more ENDOCRINE GLANDS that secrete PEPTIDE HORMONES or AMINES. These neoplasias are often benign but can be malignant. They are classified by the endocrine glands involved and the degree of aggressiveness. The two major forms are MEN1 and MEN2 with gene mutations on CHROMOSOME 11 and CHROMOSOME 10, respectively.   MeSH

Subtype Terms (3)

Multiple Endocrine Neoplasia Type 1
8 drugs (7 approved, 1 experimental)

Multiple Endocrine Neoplasia Type 2a
5 drugs (4 approved, 1 experimental)

Multiple Endocrine Neoplasia Type 2b
5 drugs (4 approved, 1 experimental)


Phase 4 Indicated Drugs (1)


Organization Involved with Phase 4 Indications (2)

Hierarchy Tree View

UMLS Data


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