Related MeSH Hierarchy (8)
Diseases [C] » Endocrine System Diseases [C19] » Gonadal Disorders » Disorders of Sex Development » Sex Chromosome Disorders of Sex Development » Klinefelter Syndrome
Diseases [C] » Endocrine System Diseases [C19] » Gonadal Disorders » Hypogonadism » Klinefelter Syndrome
Diseases [C] » Urogenital Diseases [C12] » Female Urogenital Diseases and Pregnancy Complications » Female Urogenital Diseases » Urogenital Abnormalities » Disorders of Sex Development » Sex Chromosome Disorders of Sex Development » Klinefelter Syndrome
Diseases [C] » Urogenital Diseases [C12] » Male Urogenital Diseases » Urogenital Abnormalities » Disorders of Sex Development » Sex Chromosome Disorders of Sex Development » Klinefelter Syndrome
Diseases [C] » Urogenital Diseases [C12] » Urogenital Abnormalities » Disorders of Sex Development » Sex Chromosome Disorders of Sex Development » Klinefelter Syndrome
Diseases [C] » Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16] » Genetic Diseases, Inborn » Chromosome Disorders » Sex Chromosome Disorders » Sex Chromosome Disorders of Sex Development » Klinefelter Syndrome
Diseases [C] » Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16] » Congenital Abnormalities » Chromosome Disorders » Sex Chromosome Disorders » Sex Chromosome Disorders of Sex Development » Klinefelter Syndrome
Diseases [C] » Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16] » Congenital Abnormalities » Urogenital Abnormalities » Disorders of Sex Development » Sex Chromosome Disorders of Sex Development » Klinefelter Syndrome
Description
A form of male HYPOGONADISM, characterized by the presence of an extra X CHROMOSOME, small TESTES, seminiferous tubule dysgenesis, elevated levels of GONADOTROPINS, low serum TESTOSTERONE, underdeveloped secondary sex characteristics, and male infertility (INFERTILITY, MALE). Patients tend to have long legs and a slim, tall stature. GYNECOMASTIA is present in many of the patients. The classic form has the karyotype 47,XXY. Several karyotype variants include 48,XXYY; 48,XXXY; 49,XXXXY, and mosaic patterns ( 46,XY/47,XXY; 47,XXY/48,XXXY, etc.). MeSH
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Approved Indicated Drugs (1)
Phase 2 Indicated Drugs (3)
Other Experimental Indicated Drugs (2)
Organization Involved with Phase 4 Indications (1)
Organization Involved with Phase 3 Indications (1)
Organization Involved with Phase 2 Indications (3)
Organization Involved with Other Experimental Indications (4)
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UMLS Data
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