Chemicals and Drugs [D] » Enzymes and Coenzymes [D08] » Cytochromes
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Hemeproteins » Cytochromes
Description
Hemeproteins whose characteristic mode of action involves transfer of reducing equivalents which are associated with a reversible change in oxidation state of the prosthetic group. Formally, this redox change involves a single-electron, reversible equilibrium between the Fe(II) and Fe(III) states of the central iron atom (From Enzyme Nomenclature, 1992, p539). The various cytochrome subclasses are organized by the type of HEME and by the wavelength range of their reduced alpha-absorption bands. MeSH
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Subtype Terms (6)
Cytochrome P-450 Enzyme System
8 drugs (7 approved, 1 experimental)
Phase 1 Indicated Drugs (2)
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