Related MeSH Hierarchy (4)
Chemicals and Drugs [D] » Organic Chemicals [D02] » Aza Compounds » Azabicyclo Compounds » Tropanes » Cocaine
Chemicals and Drugs [D] » Heterocyclic Compounds [D03] » Alkaloids » Tropanes » Cocaine
Chemicals and Drugs [D] » Heterocyclic Compounds [D03] » Heterocyclic Compounds, Bridged-Ring » Bridged Bicyclo Compounds, Heterocyclic » Azabicyclo Compounds » Tropanes » Cocaine
Chemicals and Drugs [D] » Heterocyclic Compounds [D03] » Heterocyclic Compounds, Bridged-Ring » Tropanes » Cocaine
Description
An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse. Cocaine, like amphetamines, acts by multiple mechanisms on brain catecholaminergic neurons; the mechanism of its reinforcing effects is thought to involve inhibition of dopamine uptake. MeSH
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Subtype Terms (1)
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