Related MeSH Hierarchy (5)
Diseases [C] » Infections [C01] » Virus Diseases » Tumor Virus Infections » Epstein-Barr Virus Infections » Burkitt Lymphoma
Diseases [C] » Neoplasms [C04] » Neoplasms by Histologic Type » Lymphoma » Lymphoma, Non-Hodgkin » Lymphoma, B-Cell » Burkitt Lymphoma
Diseases [C] » Hemic and Lymphatic Diseases [C15] » Lymphatic Diseases » Lymphoproliferative Disorders » Lymphoma » Lymphoma, Non-Hodgkin » Lymphoma, B-Cell » Burkitt Lymphoma
Diseases [C] » Infections [C01] » Virus Diseases » DNA Virus Infections » Herpesviridae Infections » Epstein-Barr Virus Infections » Burkitt Lymphoma
Diseases [C] » Immune System Diseases [C20] » Immunoproliferative Disorders » Lymphoproliferative Disorders » Lymphoma » Lymphoma, Non-Hodgkin » Lymphoma, B-Cell » Burkitt Lymphoma
Description
A form of undifferentiated malignant LYMPHOMA usually found in central Africa, but also reported in other parts of the world. It is commonly manifested as a large osteolytic lesion in the jaw or as an abdominal mass. B-cell antigens are expressed on the immature cells that make up the tumor in virtually all cases of Burkitt lymphoma. The Epstein-Barr virus (HERPESVIRUS 4, HUMAN) has been isolated from Burkitt lymphoma cases in Africa and it is implicated as the causative agent in these cases; however, most non-African cases are EBV-negative. MeSH
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Approved Indicated Drugs (1)
Phase 2 Indicated Drugs (74)
allogeneic epstein-barr virus specific cytotoxic t-lymphocytes
allogeneic hematopoietic stem cells (Hemacord)
Anti-thymocyte Globulin (Rabbit) (Thymoglobulin)
autologous cd34+ cells transduced withpsrs11.efs.il2rg.pre
autologous ebv specific cytotoxic t lymphocytes
Other Experimental Indicated Drugs (13)
Organization Involved with Phase 4 Indications (4)
Organization Involved with Phase 2 Indications (56)
Badalona Hospital Germans Trias i Pujol
Case Western Reserve University
Gesellschaft fur Medizinische Innovation – Hamatologie und Onkologie mbH
Medical City Children's Hospital, Dallas
Organization Involved with Phase 1 Indications (22)
Organization Involved with Other Experimental Indications (2)
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UMLS Data
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