Buprenorphine D002047

Related MeSH Hierarchy (4)

Chemicals and Drugs [D] » Heterocyclic Compounds [D03] » Alkaloids » Opiate Alkaloids » Morphinans » Buprenorphine

Chemicals and Drugs [D] » Heterocyclic Compounds [D03] » Heterocyclic Compounds, Bridged-Ring » Morphinans » Buprenorphine

Chemicals and Drugs [D] » Polycyclic Compounds [D04] » Polycyclic Aromatic Hydrocarbons » Phenanthrenes » Morphinans » Buprenorphine

Description

A derivative of the opioid alkaloid THEBAINE that is a more potent and longer lasting analgesic than MORPHINE. It appears to act as a partial agonist at mu and kappa opioid receptors and as an antagonist at delta receptors. The lack of delta-agonist activity has been suggested to account for the observation that buprenorphine tolerance may not develop with chronic use.   MeSH

Hierarchy View


Phase 1 Indicated Drugs (1)

Hierarchy Tree View


YOU AGREE THAT THE INFORMATION PROVIDED ON THIS WEBSITE IS PROVIDED “AS IS”, WITHOUT ANY WARRANTY OF ANY KIND, EXPRESSED OR IMPLIED, INCLUDING WITHOUT LIMITATION WARRANTIES OF MERCHANTABILITY OR FITNESS FOR ANY PARTICULAR PURPOSE, OR NON-INFRINGEMENT OF ANY THIRD-PARTY PATENT, COPYRIGHT, OR ANY OTHER THIRD-PARTY RIGHT. IN NO EVENT SHALL THE CREATORS OF THE WEBSITE OR WASHINGTON UNIVERSITY BE LIABLE FOR ANY DIRECT, INDIRECT, SPECIAL, OR CONSEQUENTIAL DAMAGES ARISING OUT OF OR IN ANY WAY CONNECTED WITH THE WEBSITE, THE USE OF THE WEBSITE, OR THIS AGREEMENT, WHETHER IN BREACH OF CONTRACT, TORT OR OTHERWISE, EVEN IF SUCH PARTY IS ADVISED OF THE POSSIBILITY OF SUCH DAMAGES.