Arachidonate Lipoxygenases D001091

Chemicals and Drugs [D] » Enzymes and Coenzymes [D08] » Enzymes » Oxidoreductases » Oxygenases » Dioxygenases » Lipoxygenases » Arachidonate Lipoxygenases

Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Metalloproteins » Iron-Binding Proteins » Nonheme Iron Proteins » Lipoxygenases » Arachidonate Lipoxygenases

Description

Enzymes catalyzing the oxidation of arachidonic acid to hydroperoxyarachidonates. These products are then rapidly converted by a peroxidase to hydroxyeicosatetraenoic acids. The positional specificity of the enzyme reaction varies from tissue to tissue. The final lipoxygenase pathway leads to the leukotrienes. EC 1.13.11.- .   MeSH

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