Chemicals and Drugs [D] » Chemical Actions and Uses [D27] » Pharmacologic Actions » Molecular Mechanisms of Pharmacological Action » Enzyme Inhibitors » Protease Inhibitors » Angiotensin-Converting Enzyme Inhibitors
A class of drugs whose main indications are the treatment of hypertension and heart failure. They exert their hemodynamic effect mainly by inhibiting the renin-angiotensin system. They also modulate sympathetic nervous system activity and increase prostaglandin synthesis. They cause mainly vasodilation and mild natriuresis without affecting heart rate and contractility. MeSH
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