Diseases [C] » Nutritional and Metabolic Diseases [C18] » Metabolic Diseases » Proteostasis Deficiencies » Amyloidosis
Description
A group of sporadic, familial and/or inherited, degenerative, and infectious disease processes, linked by the common theme of abnormal protein folding and deposition of AMYLOID. As the amyloid deposits enlarge they displace normal tissue structures, causing disruption of function. Various signs and symptoms depend on the location and size of the deposits. MeSH
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Subtype Terms (4)
Amyloid Neuropathies
3 drugs (1 approved, 2 experimental)
Amyloidosis, Familial
6 drugs (3 approved, 3 experimental)
Cerebral Amyloid Angiopathy
5 drugs (1 approved, 4 experimental)
Immunoglobulin Light-chain Amyloidosis
51 drugs (40 approved, 11 experimental)
Approved Indicated Drugs (3)
Phase 4 Indicated Drugs (2)
Phase 3 Indicated Drugs (18)
Phase 2 Indicated Drugs (15)
Phase 1 Indicated Drugs (11)
Organization Involved with Phase 4 Indications (8)
Organization Involved with Phase 3 Indications (38)
Organization Involved with Phase 2 Indications (53)
Cancer and Leukemia Group B (CALGB)
Chinese Academy of Medical Sciences
City of Hope National Medical Center
Eastern Cooperative Oncology Group
German Federal Ministry of Education and Research
Hellenic Cooperative Oncology Group
Herbert Irving Comprehensive Cancer Center
Hoosier Cancer Research Network
Icahn School of Medicine at Mount Sinai
Memorial Sloan-Kettering Cancer Center
Multiple Myeloma Research Consortium
Organization Involved with Phase 1 Indications (14)
Organization Involved with Other Experimental Indications (13)
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UMLS Data
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