Related MeSH Hierarchy (9)
Diseases [C] » Urogenital Diseases [C12] » Female Urogenital Diseases and Pregnancy Complications » Female Urogenital Diseases » Urogenital Abnormalities » Disorders of Sex Development » Adrenogenital Syndrome » Adrenal Hyperplasia, Congenital
Diseases [C] » Urogenital Diseases [C12] » Male Urogenital Diseases » Urogenital Abnormalities » Disorders of Sex Development » Adrenogenital Syndrome » Adrenal Hyperplasia, Congenital
Diseases [C] » Urogenital Diseases [C12] » Urogenital Abnormalities » Disorders of Sex Development » Adrenogenital Syndrome » Adrenal Hyperplasia, Congenital
Diseases [C] » Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16] » Congenital Abnormalities » Urogenital Abnormalities » Disorders of Sex Development » Adrenogenital Syndrome » Adrenal Hyperplasia, Congenital
Diseases [C] » Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16] » Genetic Diseases, Inborn » Adrenal Hyperplasia, Congenital
Diseases [C] » Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16] » Genetic Diseases, Inborn » Metabolism, Inborn Errors » Steroid Metabolism, Inborn Errors » Adrenal Hyperplasia, Congenital
Diseases [C] » Nutritional and Metabolic Diseases [C18] » Metabolic Diseases » Metabolism, Inborn Errors » Steroid Metabolism, Inborn Errors » Adrenal Hyperplasia, Congenital
Diseases [C] » Endocrine System Diseases [C19] » Adrenal Gland Diseases » Adrenal Hyperplasia, Congenital
Diseases [C] » Endocrine System Diseases [C19] » Gonadal Disorders » Disorders of Sex Development » Adrenogenital Syndrome » Adrenal Hyperplasia, Congenital
Description
A group of inherited disorders of the ADRENAL GLANDS, caused by enzyme defects in the synthesis of cortisol (HYDROCORTISONE) and/or ALDOSTERONE leading to accumulation of precursors for ANDROGENS. Depending on the hormone imbalance, congenital adrenal hyperplasia can be classified as salt-wasting, hypertensive, virilizing, or feminizing. Defects in STEROID 21-HYDROXYLASE; STEROID 11-BETA-HYDROXYLASE; STEROID 17-ALPHA-HYDROXYLASE; 3-beta-hydroxysteroid dehydrogenase (3-HYDROXYSTEROID DEHYDROGENASES); TESTOSTERONE 5-ALPHA-REDUCTASE; or steroidogenic acute regulatory protein; among others, underlie these disorders. MeSH
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Phase 4 Indicated Drugs (2)
Phase 3 Indicated Drugs (1)
Phase 2 Indicated Drugs (6)
Phase 1 Indicated Drugs (1)
Other Experimental Indicated Drugs (1)
Organization Involved with Phase 4 Indications (2)
Organization Involved with Phase 3 Indications (3)
Organization Involved with Phase 2 Indications (12)
Organization Involved with Phase 1 Indications (3)
Organization Involved with Other Experimental Indications (2)
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UMLS Data
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