Chemicals and Drugs [D] » Enzymes and Coenzymes [D08] » Enzymes » Oxidoreductases » NADH, NADPH Oxidoreductases » NADPH Oxidases » NADPH Oxidase 2
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Flavoproteins » NADPH Oxidases » NADPH Oxidase 2
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Membrane Proteins » NADPH Oxidases » NADPH Oxidase 2
An NADPH oxidase that is expressed by PHAGOCYTES where it transfers electrons across the plasma membrane from cytosolic NADPH to molecular oxygen on the exterior. It regulates proton (H+) flux into resting phagocytes to control intracellular pH. Mutations in the CYBB gene are associated with X-LINKED CHRONIC GRANULOMATOUS DISEASE. MeSH
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