DNA Ligase ATP D000072481

Chemicals and Drugs [D] » Enzymes and Coenzymes [D08] » Enzymes » DNA Repair Enzymes » DNA Ligases » DNA Ligase ATP

Chemicals and Drugs [D] » Enzymes and Coenzymes [D08] » Enzymes » Ligases » Polynucleotide Ligases » DNA Ligases » DNA Ligase ATP

Description

ATP-dependent cellular enzyme which catalyzes DNA replication, repair and recombination through formation of internucleotide ester bonds between phosphate and deoxyribose moieties. Vertebrate cells encode three well-characterized DNA ligases, DNA ligase I, III and IV, all of which are related in structure and sequence. DNA ligases either require ATP or NAD. However, archaebacterial, viral, and some eubacterial DNA ligases are ATP-dependent.   MeSH

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