Ku Autoantigen D000072200

Related MeSH Hierarchy (7)

Chemicals and Drugs [D] » Enzymes and Coenzymes [D08] » Enzymes » Hydrolases » Acid Anhydride Hydrolases » Adenosine Triphosphatases » DNA Helicases » Ku Autoantigen

Chemicals and Drugs [D] » Enzymes and Coenzymes [D08] » Enzymes » Isomerases » DNA Helicases » Ku Autoantigen

Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Carrier Proteins » Poly-ADP-Ribose Binding Proteins » Ku Autoantigen

Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Nuclear Proteins » Antigens, Nuclear » Ku Autoantigen

Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Nuclear Proteins » Poly-ADP-Ribose Binding Proteins » Ku Autoantigen

Chemicals and Drugs [D] » Biological Factors [D23] » Antigens » Antigens, Nuclear » Ku Autoantigen

Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » DNA-Binding Proteins » Ku Autoantigen

Description

An ATP-dependent DNA HELICASE that preferentially binds SINGLE-STRANDED DNA. It is a heterodimer consisting of an 80 kDa subunit (XRCC5) and 70 kDa subunit (XRCC6) that functions with DNA LIGASE IV in the repair of DOUBLE-STRANDED DNA BREAKS and V(D)J RECOMBINATION.   MeSH

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