Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Glycoproteins » Membrane Glycoproteins » Signaling Lymphocytic Activation Molecule Family » Signaling Lymphocytic Activation Molecule Family Member 1
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Membrane Proteins » Membrane Glycoproteins » Signaling Lymphocytic Activation Molecule Family » Signaling Lymphocytic Activation Molecule Family Member 1
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Membrane Proteins » Receptors, Cell Surface » Receptors, Immunologic » Signaling Lymphocytic Activation Molecule Family » Signaling Lymphocytic Activation Molecule Family Member 1
Description
A 70-kDa SLAM family receptor that consists of an extracellular IMMUNOGLOBULIN-LIKE DOMAIN and an IMMUNOGLOBULIN C2-SET DOMAIN. It is expressed primarily by THYMOCYTES and activated T-LYMPHOCYTES, as well as by MACROPHAGES and DENDRITIC CELLS. It binds SLAMF1 receptors on other cells to mediate T-cell maturation and proliferation. It is also a receptor for the MEASLES VIRUS. MeSH
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