Active Ingredient History
The smallpox vaccine is the first vaccine to have been developed against a contagious disease. In 1796, British physician Edward Jenner demonstrated that an infection with the relatively mild cowpox virus conferred immunity against the deadly smallpox virus. Cowpox served as a natural vaccine until the modern smallpox vaccine emerged in the 20th century. From 1958 to 1977, the World Health Organization (WHO) conducted a global vaccination campaign that eradicated smallpox, making it the only human disease to be eradicated. Although routine smallpox vaccination is no longer performed on the general public, the vaccine is still being produced to guard against bioterrorism, biological warfare, and mpox. Wikipedia
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
Carcinoma, Basal Cell (Phase 1/Phase 2)
Carcinoma, Squamous Cell (Phase 1/Phase 2)
Dermatitis, Atopic (Phase 2)
HIV Infections (Phase 2)
Melanoma (Phase 1/Phase 2)
Monkeypox virus (Phase 3)
Rhinitis, Allergic, Seasonal (Phase 1)
Smallpox (Phase 3)
Smallpox Vaccine (Phase 2)
Vaccination (Phase 4)
| Trial | Phase | Start Date | Organizations | Indications |
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