Active Ingredient History

  • Now
Histidine is an essential amino acid. L-histidine is converted to histamine by histidine decarboxylase, a pyridoxal 5'-phosphate-dependent enzyme. The copper(II)–l-histidine (1:2 complex at physiological pH) has been widely used in the treatment of Menkes disease (a genetic neurodegenerative disorder that leads to early death in the children due to impaired copper metabolism) and more recent use has been reported in the treatment of infantile hypertrophic cardioencephalomyopathy (a condition caused by mutations in SCO2, a cytochrome c oxidase assembly gene). CUSTODIOL HTK (Histidine-tryptophan-ketoglutarate) Solution is indicated for perfusion and flushing of donor kidneys, liver, and heart prior to removal from the donor or immediately after removal from the donor.   NCATS

  • SMILES: N[C@@H](CC1=CNC=N1)C(O)=O
  • Mol. Mass: 155.1546
  • ALogP: -0.64
  • ChEMBL Molecule:
More Chemistry
h | his | histidine | l-histidin | l-histidine | l-(-)-histidine | l-(−)-histidine | (s)-4-(2-amino-2-carboxyethyl)imidazole | (s)-a-amino-1h-imidazole-4-propanoic acid | (s)-alpha-amino-1h-imidazole-4-propanoic acid | (s)-alpha-amino-1h-imidazole-4-propionic acid | (s)-α-amino-1h-imidazole-4-propanoic acid


Data collection and curation is an ongoing process for CDEK - if you notice any information here to be missing or incorrect, please let us know! When possible, please include a source URL (we verify all data prior to inclusion).

Report issue