API | fezolinetant

fezolinetant Report issue

Small molecule Experimental

AACT PubChem

Active Ingredient History

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Fezolinetant (INN; former developmental code name ESN-364) is a small-molecule, orally active, selective neurokinin-3 (NK3) receptor antagonist which is under development by Ogeda (formerly Euroscreen) for the treatment of sex hormone-related disorders. As of May 2017, it has completed phase I and phase IIa clinical trials for hot flashes in postmenopausal women. Phase IIa trials in polycystic ovary syndrome patients are ongoing. In April 2017, it was announced that Ogeda would be acquired by Astellas Pharma. ^Wikipedia

Chemistry

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Pharmacology

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fezolinetant

Organizations (2)

Research & Development (2)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Marketing (0)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Indications (6)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (6)

Healthy Volunteers (Phase 1)

Hot Flashes (Phase 3)

Kidney Failure, Chronic (Phase 1)

Liver Diseases (Phase 1)

Menopause (Phase 2)

Vasomotor System (Phase 3)

Overview

Highest Phase: Phase 3
# of Trials: 15
# of Trial Organizations: 2

Trials by Phase

Trial	Phase	Start Date	Organizations	Indications

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