Active Ingredient History

  • Now
Carvedilol competitively blocks β1, β2 and α1 receptors. The drug lacks sympathomimetic activity and has vasodilating properties that are exerted primarily through α1-blockade. Animal models indicate that carvedilol confers protection against myocardial necrosis, arrhythmia and cell damage caused by oxidising free radicals, and the drug has no adverse effects on plasma lipid profiles. COREG® (carvedilol) is a racemic mixture in which nonselective β-adrenoreceptor blocking activity is present in the S(-) enantiomer and α1-adrenergic blocking activity is present in both R(+) and S(-) enantiomers at equal potency. Carvedilol is the first drug of its kind to be approved for the treatment of congestive heart failure, and is now the standard of care for this devastating disease. Carvedilol is also confirmed as effective in the management of mild to moderate hypertension and ischaemic heart disease.   NCATS

  • SMILES: COc1ccccc1OCCNCC(O)COc2cccc3[nH]c4ccccc4c23
  • Mol. Mass: 406.48
  • ALogP: 3.74
  • ChEMBL Molecules:
More Chemistry

Drug Pricing (per unit)

United States

$0.0097 - $8.7792


$0.0837 - $0.1739
More Pricing Detail

Note: This drug pricing data is preliminary, incomplete, and may contain errors.

(+-)-1-(carbazol-4-yloxy)-3-((2-(o-methoxyphenoxy)ethyl)amino)-2-propanol | bm 14190 | bm 14,190 | bm 14.190 | bm-14190 | bm-14-190 | bm-14.190 | carvedilol | carvedilol, 14c-labeled | carvedilol hcl | carvedilol hydrochloride | carvedilol, (+-)-isomer | carvedilol phosphate | carvedilol phosphate hemihydrate | carvedilol, (r)-isomer | carvedilol, (s)-isomer | carvedilol sulfate | carvedilolum | carvediol | coreg | coreg cr | coropres | dilatrend | eucardic | eucardic 12.5 | eucardic 25 | eucardic 3.125 | eucardic 6.25 | kredex | querto | skf 105517 | sk&f-105517-d


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