Active Ingredient History

  • Now
Zosuquidar is an experimental antineoplastic drug. Zosquidir inhibits P-glycoproteins. Other drugs with this mechanism include tariquidar and laniquidar. P-glycoproteins are trans-membrane proteins that pump foreign substances out of cells in an ATP dependent fashion. Cancers overexpressing P-glycoproteins are able to pump out therapeutic molecules before they are able to reach their target, effectively making the cancer multi-drug resistant. Zosuquidar inhibits P-glycoproteins, inhibiting the efflux pump and restoring sensitivity to chemotherapeutic agents.   Wikipedia

  • SMILES: O[C@@H](COc1cccc2ncccc12)CN3CCN(CC3)[C@H]4c5ccccc5[C@H]6[C@@H](c7ccccc47)C6(F)F
  • Mol. Mass: 527.62
  • ALogP: 5.21
  • ChEMBL Molecule:
More Chemistry


Data collection and curation is an ongoing process for CDEK - if you notice any information here to be missing or incorrect, please let us know! When possible, please include a source URL (we verify all data prior to inclusion).

Report issue